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Andre Agassi defeated Roger Federer in the 2005 US Open final with a score of 6-3, 2-6, 7-6(1), 6-1. This was Federer's only US Open final loss (he won 5 straight titles from 2004-2008). Agassi's victory was particularly significant as it came late in his career and prevented Federer from completing a Calendar Year Grand Slam (Federer had already won the Australian Open, Wimbledon, and French Open that year).