Human genome project - class-XI

human genome project

46 Questions Published

Questions

Question 1 Multiple Choice (Single Answer)

Which out of the following statements is incorrect?

  1. Genetic code is ambiguous.
  2. Genetic code is degenerate.
  3. Genetic code is universal.
  4. Genetic code is non-overlapping.
Question 2 Multiple Choice (Single Answer)

Choose the correct answer from the alternatives given, Human genome consists of approximately

  1. $3 \, \times \, 10^9$ bp
  2. $6 \, \times \, 10^9$ bp
  3. 20,000 + 25,000 bp
  4. $2.2 \, \times \, 10^4$ bp
Question 3 Multiple Choice (Single Answer)

Choose the correct answer from the alternatives given :
Which of the following statements regarding human genome is incorrect?

  1. Human genome consists of $3 \, \times \, 10^9$ bp and about 20,500 genes.
  2. The average gene size is 3000 bop and dystrophin is the largest known human gene.
  3. Chromosome 1 contains maximum (2968) number of genes and Y-chrbmosome has the least (231) number of genes.
  4. Repeated (or repetitive) sequences are not present in human genome.
Question 4 Multiple Choice (Single Answer)

All living organism present past and future are 

  1. Not linked to any extent
  2. Linked to one another in their cell membrane
  3. Linked to one another by the sharing of the common genetic materials ,but to varying degrees
  4. Linked to another by the sharing of the common genetic material to $100\%$ extent
Question 5 Multiple Choice (Single Answer)

Which of the following is an application  of human genome project?

  1. Understanding of phylogenetic disorder
  2. Improvement in gene therapy
  3. Understanding of mutation concept
  4. All of the above
Question 6 Multiple Choice (Single Answer)

The genome of Caenorhabditis elgans consists of

  1. 3 billion base pairs and 30,000 genes
  2. 180 million base pairs and 13,000 genes
  3. 4.7 million base pairs and 4,000 genes
  4. 97 million base pairs and 18,000 genes
  5. 12 million base pairs and 6,000 genes
Question 7 Multiple Choice (Single Answer)

Number of genes believed to be present in a human being is

  1. 1000
  2. 10,000
  3. 100,000
  4. 1,000,000
Question 8 Multiple Choice (Single Answer)

Genetic code translates the language of __________________.

  1. Amino acids into that of RNA
  2. RNA into that of protein
  3. Protein into that of DNA
  4. RNA into that of DNA
Question 9 Multiple Choice (Single Answer)

Nucleotide pairs present in human genes vary between

  1. 100 - 1000
  2. 500 - 5000
  3. 2000 - 2,000,000
  4. 10,000 - 10,000,000
Question 10 Multiple Choice (Single Answer)

Total number of base pairs found in human genome is?

  1. $3.5$ million
  2. $35000$
  3. $35$ billion
  4. $3.1$ billion
Question 11 Multiple Choice (Single Answer)

According to finding from the Human Genome Project, there are about 25000 genes but there are amny more different polypeptides. Which of the following processes might explain the discrepancy between number of genes and polypeptides?
(1) Mutations
(2) Post-translational modifications
(3) Crossing over during meiosis
(4) Alternating splicing of RNA transcripts

  1. 1 & 2
  2. 2 & $
  3. 1,3 & 4
  4. 3 & 4
Question 12 Multiple Choice (Single Answer)

The commonly used hosts in HGP ________________.

  1. Bacteria and yeast
  2. Bacteria and fungi
  3. Protozoa and bacteria
  4. Plants and fungi
Question 13 Multiple Choice (Single Answer)

Select the wrong statement.

  1. The human genome contains $3164.7$ million nucleotide bases
  2. Less than $10\%$ of the genome codes for protein
  3. Repeated sequences make up very large portion of the human genome
  4. Chromosome $1$ has most genes $(2968)$ and Y has the fewest $(231)$
Question 14 Multiple Choice (Single Answer)

The total number of nitrogenous bases in human genom is estimated to be about

  1. 3.5 million
  2. 35 thousand
  3. 35 million
  4. 3.3 billion
Question 15 Multiple Choice (Single Answer)

The most detailed genetic map is 

  1. Cytogenetic
  2. Linkage
  3. Physical
  4. Sequence
Question 16 Multiple Choice (Single Answer)

Which of the following is the largest gene in humans?

  1. Dystrophin
  2. Insulin
  3. Titin
  4. Phosphofructokinase
Question 17 Multiple Choice (Single Answer)

Which of the following can improve the diagnosis of many genetic disorder?

  1. PCR
  2. Human genome project
  3. DNA fingerprinting
  4. None of the above
Question 18 Multiple Choice (Single Answer)

Which of the following is not an aim of human genome project?

  1. To sequence the genome of selected model organism
  2. Eliminate all disease
  3. To sequence EST fragments of cDNA in both human and mice
  4. To develop computational tool for analysing sequence information
Question 19 Multiple Choice (Single Answer)

Lily has .......... more DNA than human genome.

  1. 10 times
  2. 4 times
  3. 20 times
  4. 18 times
Question 20 Multiple Choice (Single Answer)

Which of the following provides fund for the human genome project?

  1. NIH
  2. DOE
  3. Both A and B
  4. NIH, DOE and ELSI
Question 21 Multiple Choice (Single Answer)

Human genome project was

discovered by

  1. Francis Collins and Roderick
  2. Watson and Crick
  3. Beadle and Tatum
  4. Paul Berg and Wollman
Question 22 Multiple Choice (Single Answer)

Human genome project was launched in

  1. 1980
  2. 1987
  3. 1990
  4. 1993
Question 23 Multiple Choice (Single Answer)

Human genome contains base pairs

  1. 2.5 million
  2. 25 million
  3. 27.2 million
  4. 3.2 billion
Question 24 Multiple Choice (Single Answer)

Human genome project was launched by 

  1. Khorana and others
  2. Bhabha Institute
  3. U.S Department of Energy and National Institute of Health
  4. NASA
Question 25 Multiple Choice (Single Answer)

Number of genes present in human genome is about

  1. 15,000
  2. 21,000
  3. 27,000
  4. 30,000
Question 26 Multiple Choice (Single Answer)

A ribotide is made of

  1. Adenine + Deoxyribose + Phosphate
  2. Uracil + Ribose + Phosphate
  3. Thymine + Ribose + Phosphate
  4. Uracil + Deoxyribose + Phosphate
Question 27 Multiple Choice (Single Answer)

Which is false ? 

  1. A/T is one
  2. A + G = C + T
  3. C/G is one
  4. A + T = C + G
Question 28 Multiple Choice (Single Answer)

Which ones are degenerate codons ?

  1. UAA, UAG and UGA
  2. GUA, GUG, GCA, GCG and GAA
  3. UUC, UUG, CCU, CAA and CUA
  4. UUA, UUG, CUU, CUC, CUA and CUG
  5. AAC, AAG, GAC and CGG
Question 29 Multiple Choice (Single Answer)

Condensation product of adenine, ribose and phosphoric acid is

  1. Adenylic acid
  2. Adenine phosphate
  3. Adenosine
  4. None of the above
Question 30 Multiple Choice (Single Answer)

Number of histone molecules in each nucleosome core is

  1. 14
  2. 12
  3. 10
  4. 8
Question 31 Multiple Choice (Single Answer)

If the codon GGU is reversed, the resulting codon will code for amino acid

  1. Tyr
  2. Trp
  3. Leu
  4. Thr
Question 32 Multiple Choice (Single Answer)

Choose the wrong statement regarding the observation drawn from Human Genome Project

  1. Repetitive sequences are stretches of RNA
  2. Less than 2% of the genome codes for protein
  3. Chromosome Y has the fewest number of genes
  4. SNPs help in tracing human history
  5. Repetive sequences make up a very large portion of the human genome
Question 33 Multiple Choice (Single Answer)

How many sense codons code for 20 human essential amino acids

  1. 61
  2. 62
  3. 63
  4. 64
Question 34 Multiple Choice (Single Answer)

Human genome project (HGP) was initiated in

  1. 1988
  2. 1990
  3. 1992
  4. 1994
Question 35 Multiple Choice (Single Answer)

Human genome project was started in

  1. $1989$
  2. $1990$
  3. $1992$
  4. $1995$
Question 36 Multiple Choice (Single Answer)

As per latest information human genome has

  1. $3,00,000$ genes
  2. $20,000$ genes
  3. $3,000$ genes
  4. $300$ genes
Question 37 Multiple Choice (Single Answer)

Main aim of human genome project is to

  1. Introduce new genes into human beings.
  2. Identify and sequence all the genes present in human DNA.
  3. Develop better techniques to compare two human DNAs.
  4. Remove disease causing genes from human DNA.
Question 38 Multiple Choice (Single Answer)

The state in which the viral genome gets integrated with the bacterial genome is called.

  1. Prophage
  2. Prophase
  3. Adsorption
  4. Lysogeny
Question 39 Multiple Choice (Single Answer)

The human genome contains (a) billion nucleotide bases. The average gene consists of (b) bases. Which option is correct for a & b?

  1. $a = 3, b = 3000$
  2. $a = 5, b = 3000$
  3. $a = 3, b = 2000$
  4. $a = 4, b = 3000$
Question 40 Multiple Choice (Single Answer)

All of the following except are sources of change in the genome

  1. Nondisjunction during meiosis
  2. Gene mutations
  3. Crossing over
  4. Amniocentesis
Question 41 Multiple Choice (Single Answer)

The human genome project involves all of the following except

  1. altering the human genome
  2. physical mapping of the chromosomes
  3. sequencing of the entire nucleotide sequence of the human genome
  4. location of RFLP markers
Question 42 Multiple Choice (Single Answer)

The sequencing of the entire genome (the totality of all genes) of an organism was completed in 1996. The organism was

  1. Human being
  2. Yeast
  3. Albino mouse
  4. Plasmodium vivax
Question 43 Multiple Choice (Single Answer)

The whole genome of Escherichia coli having $4.6\times 10^6$ bp will be replaced in?

  1. $2$ minutes
  2. One hour
  3. $40$ minutes
  4. $38$ minutes
Question 44 Multiple Choice (Single Answer)

Human Genome Project is under the control of Human Genome Organization which is funded primarily by

  1. NIH in USA
  2. DOE in USA
  3. EC in Europe
  4. All of the above
Question 45 Multiple Choice (Single Answer)

Human genome project was discovered by

  1. Francis Collins and Roderick
  2. Watson and Crick
  3. Beadle and Tatum
  4. Paul Berg and Wollman