Home › Quizzes › Molecular Human Genetics

Molecular Human Genetics

This quiz tests knowledge of molecular genetic mechanisms including mutation types, DNA damage and repair, genetic disorders, and nucleic acid metabolism in human genetics.

14 Questions Published
Play Quiz Practise this topic out loud

Questions

Question 1 Multiple Choice (Single Answer)

Mrs. Verma is a diabetic patient for the past three years. Diabetes is an example of which of the following disorders?

  1. Chromosomal disease
  2. Single-gene disorder
  3. Multifactorial disorder
  4. Mitochondrial disorder
  5. Trinucleotide repeat disorder
Question 2 Multiple Choice (Single Answer)

Which of the following genetic disorders is a sex linked disease?

  1. Sickle-cell anemia
  2. Haemophilia
  3. Cystic fibrosis
  4. Tay-Sachs disease
  5. Huntington’s disease
Question 3 Multiple Choice (Single Answer)

Scaffold proteins are crucial regulators of many key signaling pathways. The products of which of the following genes may play a role as scaffolding protein at cell–cell junctions?

  1. BAIAP2 gene
  2. MAGI1 gene
  3. MAGI2 gene
  4. RERE gene
  5. WWP2 gene
Question 4 Multiple Choice (Single Answer)

Which of the following processes is a DNA damage tolerance process?

  1. Tautomerism
  2. Depurination
  3. Deamination
  4. Slipped strand mispairing
  5. Translesion synthesis
Question 5 Multiple Choice (Single Answer)

Which of the following types of mutation is most likely to lead to premature termination of translation?

  1. Insertion of a single base into DNA
  2. Deletion of three bases from DNA
  3. Deletion of an entire gene
  4. Single base change in a promoter
  5. Exon skip
Question 6 Multiple Choice (Single Answer)

The Huntington's disease mutation is genetically dominant, because either of a person's HTT genes being mutated causes the disease. CAG/CTG repeat expansions at the Huntington's disease is associated with which of the following genes?

  1. JPH3 gene
  2. ACSF3 gene
  3. ACD gene
  4. AMFR gene
  5. CYLD gene
Question 7 Multiple Choice (Single Answer)

Which of the following is most likely to be a conservative mutation?

  1. CAA to TAA
  2. CCT to GCT
  3. ATC to GTC
  4. ATA to AAA
  5. CGA to TGA
Question 8 Multiple Choice (Single Answer)

Which of the following types of mutations is most likely to result from UV exposure?

  1. Thymidine dimer
  2. Chromosome breakage
  3. Frameshift mutation
  4. Nonsense mutations
  5. Chromosome inversion
Question 9 Multiple Choice (Single Answer)

A cDNA library contains clones representing which of the following?

  1. Micro RNA (miRNA)
  2. mRNA
  3. Genomic DNA
  4. Exon
  5. Introns
Question 10 Multiple Choice (Single Answer)

Which of the following repeated sequences includes an open reading frame for reverse transcriptase?

  1. Segmental duplication
  2. SINE
  3. LINE
  4. DNA transposon
  5. Variable number tandem repeat
Question 11 Multiple Choice (Single Answer)

Homologous repeats are involved in which of the following types of mutations?

  1. Missense mutations
  2. Splice-site mutations
  3. Large deletions
  4. Frameshifts
  5. Nonsense mutation
Question 12 Multiple Choice (Single Answer)

Which of the following nucleic acids is an intermediate in the metabolism of deoxyribonucleotides?

  1. Deoxyadenosine diphosphate
  2. Deoxycytidine diphosphate
  3. Deoxycytidine monophosphate
  4. Deoxyuridine monophosphate
  5. Deoxyguanosine
Question 13 Multiple Choice (Single Answer)

Which of the following is an antibiotic compound which inhibits nucleic acid biosynthesis in a living cell?

  1. Aganirsen
  2. Spiegelmer
  3. Phosphocreatine
  4. Pluramycin A
  5. Aminoallyl nucleotide
Question 14 Multiple Choice (Single Answer)

Which of the following types of RNA is included in the splicosome?

  1. snRNA
  2. miRNA
  3. tRNA
  4. rRNA
  5. siRNA
← Back to Quizzes