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Cell and Molecular Biology Fundamentals
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If the gene encoding the trp repressor is mutated, such that it can no longer bind tryptophan, then will the transcription of the trp operon occur?
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A
Yes, because the trp repressor can only bind the trp operon and block transcriptional initiation when it is bound to tryptophan.
💡 Explanation:
If the repressor can no longer bind tryptophan, then it cannot bind the operator and transcription of the trp operon will always be on, whether tryptophan levels in the cell are high or low.