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Antibiotics (GATE)
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Which of the following classes of antibiotics eventually leaves a bacterium unable to synthesise proteins that are vital to its growth by binding to 30S ribosomal unit?
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A
Aminoglycosides
💡 Explanation:
Aminoglycosides bind to bacterial 30S ribosomal unit inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesise proteins vital to its growth.