Chromosomal Basis of Inheritance
This quiz covers fundamental concepts of chromosomal inheritance including chromosomal theory, chromosome structure (histone and non-histone proteins), sex determination mechanisms, linkage groups, chromosomal abnormalities, genetic code, DNA structure, genetic engineering techniques, and genetic disorders. Important topic for medical entrance exams.
Questions
Who among the following observed sperm and egg?
- Strasburger
- Hartwig
- Bendon
- Waldeyer
- None of these
Who discovered episome?
- Hays and Lederberg
- Hays and Wollmann
- Jacob and Lederberg
- Jacob and Wollmann
- None of these
Who gave chromosomal theory of inheritence?
- Sutton and Bovery
- Bateson and Punnet
- Dr Lalji Singh and Dr V.K. Kashyap
- Morgan
- None of these
Which of the following statements is correct regarding histone proteins?
- They are acidic proteins and are present in prokaryotes.
- They are basic proteins and are present in prokaryotes.
- They are acidic proteins and are present in eukaryotes.
- They are basic proteins and are present in eukaryotes.
- None of these
Which non-histone protein forms central axis of chromosomes?
- Structural non-histone protein.
- Regulatory non-histone protein.
- Enzymatic non-histone protein.
- H1
- None of these.
XX-XY type of sex determination is present in __________.
- dioscorea
- sphaerocarpous
- fragaria
- moth
- all of these
Which of the following plants has the maximum number of chromosomes?
- Aulocantha
- Ophioglossum reticulatum
- Mucor
- Haplopappus gracilus
- None of these
Environmental type of sex determination is seen in ______________.
- crepidula
- hydrilla
- cockroach
- birds
- butterfly
What would be sex of drosophila with 2A + XXX genetic constitution?
- Normal male
- Normal female
- Meta male
- Intersex
- Meta female
Which of the following gave chromosomal theory of sex determination?
- Sutton and Bovery
- Wilson and Steven
- Finch and Klug
- Kornberg and Thomas
- None of these
What would be the linkage group in case of human male?
- 23
- 24
- 46
- 22
- None of these
ZZ-ZO type of sex determination is opposite to ______________.
- ZZ-ZW type
- XX-XY type
- XX-XO type
- All of these
- None of these
What will be linkage group in wheat?
- 21
- 7
- 10
- 4
- 1
Deficiency of which of the following leads to alkaptonuria?
- Tyrosinase enzyme
- Oxidase enzyme
- Hexosaminidase B
- Glucocerebrosidase enzyme
- Phenylalanine hydroxylase
Which of the following types of DNA has 11 base pairs per turn?
- B DNA
- A DNA
- C DNA
- Z DNA
- None of these
Which of the following is due to trisomy of 18 chromosomes?
- Autosomal abnormality that is Edward's syndrome
- Allosomal abnormality that is Edward's syndrome
- Autosomal abnormality that is Patau's syndrome
- Allosomal abnormality that is Patau's syndrome
- Autosomal abnormality that is down's syndrome
Who gave one gene-one polypeptide hypothesis?
- Beadle and Tatum
- Yanofsky
- Jacobson and Baltimore
- De Vries
- None of these
Which of the following is a small sized uridine rich RNA that takes part in splicing and processing of other RNAs?
- Genetic RNA
- ScRNA
- SnRNA
- tRNA
- None of these
Which enzymes help in unwinding DNA helix in prokaryotes during replication?
- Gyrase
- Helicase
- Topoisomerase
- DNA polymerase
- DNA Ligase
Genetic code is non-ambiguous except in case of _____________.
- UUA
- AUG
- UCU
- CCU
- GUG
Which antibiotic inhibits peptidyl transferase and peptide bond formation?
- Tetracycline
- Streptomycin
- Neomycin
- Chloramphenicol
- Erythromycin
Who is the father of genetic engineering?
- Cohen and Boyer
- Paul Berg
- Gamow
- Bateson
- Morgan
Which of the following restriction enzyme gives blunt end cut?
- Eco RI
- Bam HI
- Hind III
- Pvu I
- Sma I
What is name of first clone of an African toad?
- Dolly
- Gurdon
- ANDi
- Noah
- None of these
Human genome consists of _______genes.
- 4000
- 6000
- 18000
- 13000
- 30000
Which of the following has 4.7 million base pairs?
- E.coli
- Sacchromyces cereviceae
- Coaenorhabditis elegans
- Drosophila melanogaster
- None of these
What is number of genes in drosophila melanogaster?
- 4000
- 6000
- 18000
- 13000
- 30000
Who is father of DNA finger printing?
- Sir Alec Jeffreys
- Dr. Lalji Singh and Dr. V.K Kashyap
- Karry Mulis
- Paul Berg
- None of these.
__________ is known as green colour blindness.
- Protanopia
- Tritanopia
- Deuteranopia
- Daltonism
- None of these
What is the possibility of a couple to have one son and one daughter?
- 50%
- 25%
- 75%
- 100%
- None of these
How many chromonemata are present in metaphase and anaphase of cell cycle?
- 2 and 1 respectively
- 1 and 2 respectively
- 1 and 1 respectively
- 2 and 2 respectively
- None of these