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Life Sciences (GATE)

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Assertion (A): DMSO is used as a cryopreservant for mammalian cell cultures.
Reason (R): It easily penetrates cells.

Directions: In the following question, there are two statements, Assertion (A) and Reason (R). Consider both the statements independently and mark your answers as under:

1. A and R both are correct and R is the correct explanation of A.
2. A and R both are correct and R is not the correct explanation of A.
3. A is correct and R is incorrect.
4. A is incorrect and R is correct.
5. A and R both are incorrect.

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A
A is correct and R is incorrect.
💡 Explanation:

Correct answer. A is correct and R is incorrect. Dimethyl sulfoxide (DMSO) is used as a cryopreservant for mammalian cell cultures to protect cells from ice crystal induced mechanical injury. It protects cells by preventing crystallisation of water.

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