Proteins and Their Functions (GATE - XL)
Proteins and Their Functions, GATE - XL, Proteins
Questions
Which of the following proteins plays an important role in the precise interactions between photoreceptor neuronal synapse and the bipolar dendrons?
- Pikachurin
- Arp2/3
- FtsZ
- Keratin
- Elastin
In humans, which of these proteins is secreted by the cells of floor plate?
- Fibronectin
- Integrin
- F-spondin
- Selectin
- Protein Z
Which of the following proteins connect(s) the cytoskeleton of a myocyte to the surrounding extracellular matrix through the cytoplasmic membrane?
- Dystrophin
- Tubulin
- Fibronectin
- Ribonucleoprotein
- Chaperones
Which of the following pairs of 'protein - its function' is incorrectly matched?
- Antiporter - involved in secondary active transport of two or more different molecules or ions across a phospholipid membrane
- Uniporter - integral membrane protein that is involved in facilitated diffusion
- Cotransporters - downward movement of one solute from high to low concentration to move another molecule upward from low to high concentration
- Symporter - transports differing types of molecules across the cell membrane
- Antiport - two species of ion or other solutes are pumped in opposite directions across a membrane
Which of the following statements is/are incorrect about G protein-coupled receptors?
A. They are found in all eukaryotes and prokaryotes.
B. They are involved in many diseases and target approximately 40% of all modern medicinal drugs.
C. When a ligand binds to a GPCR, it causes a conformational change in the GPCR.
- Only A
- Only B
- Only C
- Only A and B
- Only B and C
Which of the following statements is/are false about DNA binding proteins?
- In humans, replication protein A is used in processes where the double helix is separated, including DNA replication, recombination and DNA repair.
- DNA-binding proteins have specific affinity for only double stranded DNA.
- Sequence-specific DNA-binding proteins generally interact with the major groove of B-DNA.
- Only 1
- Only 2
- Only 3
- Only 1 and 2
- Only 2 and 3
Match the following.
| Column – I | Column – II |
| A. CFTR | 1. Membrane protein |
| B. CRP | 2. Glycoprotein |
| C. Protein S | 3. Light-sensitive receptor protein |
| D. Rhodopsin | 4. Pentameric protein |
- A - 1, B - 2, C - 3, D - 4
- A - 1, B - 4, C - 2, D - 3
- A - 2, B - 4, C - 3, D - 1
- A - 2, B - 3, C - 4, D - 1
- A - 4, B - 1, C - 2, D - 3
Which of the following multi-functional globular proteins is/are found in all eukaroyotic cells, except nematode sperm?
- Actin
- Tubulin
- Complement proteins
- Collagen
- C1-inhibitor
Match the following.
| List – I | List – II |
| P. Histone | 1. Globular protein |
| Q. Protamine | 2. Y-shaped protein |
| R. Immunoglobulin | 3. Nuclear protein |
| S. Ferritin | 4. Alkaline protein |
- P - 1, Q - 2, R - 3, S - 4
- P - 1, Q - 3, R - 2, S - 4
- P - 2, Q - 4, R - 3, S - 1
- P - 2, Q - 3, R - 4, S - 1
- P - 4, Q - 3, R - 2, S - 1
Which of the following proteins protects from strokes and neural regeneration?
- Ependymin
- Integrin
- Cadherin
- Selectin
- NCAM
Which of the following statements is/are true about spheroproteins?
P. Spheroproteins form adducts in water, unlike fibrous or membrane proteins.
Q. The spherical structure is induced by the protein's tertiary structure.
R. Globular proteins have a mechanism for protein folding, which is nucleation condensation model.
- Only P
- Only Q
- Only R
- Only P and Q
- Only P and R
Which of the following plays an important role in maintaining the shape of erythrocytes and regulating their membrane material properties?
- Scramblase
- CFTR
- Hemeprotein
- Ependymin
- Glycophorin C
Which of the following statements is/are incorrect about acute-phase proteins?
A. The liver responds by producing a large number of acute-phase proteins.
B. Positive acute-phase proteins serve similar physiological functions for the immune system.
C. Negative acute-phase proteins decrease inflammation.
- Only A
- Only B
- Only C
- Only A and B
- Only B and C
Which of the following proteins circulating in the blood inhibits factors Xa and XIa of the clotting cascade?
- Factor XIII
- Protein Z-related protease inhibitor
- Factor VIII
- Protein S
- Protein C
Match the column – I (Proteins) with column – II (Immune system function).
| Column – I | Column – II |
| A. Alpha 2-macroglobulin | 1. Inhibitor of fibrinolysis by inhibiting plasmin |
| B. Hepcidin | 2. Induction of enzymes that degrade extracellular matrix |
| C. Serum amyloid A | 3. Opsonin on microbes |
| D. C-reactive protein | 4. Stimulates the internalisation of ferroportin |
- A - 1, B - 2, C - 3, D - 4
- A - 1, B - 4, C - 2, D - 3
- A - 2, B - 4, C - 3, D - 1
- A - 2, B - 3, C - 4, D - 1
- A - 4, B - 1, C - 2, D - 3