Molecular Biology and Genetics (GATE)

GATE

15 Questions Published

Questions

Question 1 Multiple Choice (Single Answer)

Which of the following cancers is caused by a rapid growth of abnormal WBCs, which accumulate in the bone marrow?

  1. Acute myeloid leukemia
  2. Anal cancer
  3. Astrocytoma
  4. Brainstem glioma
  5. Cutaneous T-cell lymphoma
Question 2 Multiple Choice (Single Answer)

Which of the following is a cancer of the circulatory system, especially B-cells of WBC that are found in germinal center?

  1. Burkitt's tumor
  2. Pilocytic astrocytoma
  3. Brainstem glioma
  4. Osteosarcoma
  5. Basal cell carcinoma
Question 3 Multiple Choice (Single Answer)

Which of the following cancers arises in the cerebellum, near the posterior part of the brain and includes the cerebral hemispheres and the spinal cord?

  1. Basalioma
  2. Medulloblastoma
  3. Pilocytic astrocytoma
  4. Ependymoma
  5. Breast cancer
Question 4 Multiple Choice (Single Answer)

Which of the following is a neuroendocrine tumor that originates in the cells of the neuroendocrine system?

  1. Carcinoid
  2. Esophageal cancer
  3. Extragonadal germ cell tumor
  4. Intraocular melanoma
  5. Ewing's sarcoma
Question 5 Multiple Choice (Single Answer)

Which of the following statements is/are incorrect about endometrial cancer?

  1. It is an abnormal growth of cells that have the ability to spread to other parts of the body.
  2. It is allied with exorbitant androgen unveiling, low blood pressure and diabetes.
  3. Polycystic ovary syndrome, which causes irregular or no ovulation, is associated with a higher rate of endometrial cancer.
  1. Only 1
  2. Only 2
  3. Only 3
  4. Only 1 and 2
  5. Only 1 and 3
Question 6 Multiple Choice (Single Answer)

Which of the following is a squamous cell cancer that develops in the outer portion of the female genitals?

  1. Vulvar cancer
  2. Vaginal cancer
  3. Glioma
  4. Urethral cancer
  5. Uterine cancer
Question 7 Multiple Choice (Single Answer)

Which of the following is an invasive and highly damning form of cancer that develops from striated muscle tissues?

  1. Bowel cancer
  2. Melanoma
  3. Myeloid leukemia
  4. Malignant hepatoma
  5. Rhabdomyosarcoma
Question 8 Multiple Choice (Single Answer)

Which of the following statements is/are false?

P. Esophageal cancer arises in the food pipe and gullet.
Q. Most laryngeal cancers originate in the glottis.
R. Many males with breast cancer have not inherited a BRCA mutation.

  1. Only P
  2. Only Q
  3. Only R
  4. Only P and Q
  5. Only Q and R
Question 9 Multiple Choice (Single Answer)

Which of the following is a pregnancy-related tumor and appears when cells in the womb start to procreate uncontrollably?

  1. Thymoma
  2. Gestational trophoblastic disease
  3. Thymic carcinoma
  4. Testicular cancer
  5. Neuroectodermal tumor
Question 10 Multiple Choice (Single Answer)

Which of the following statements is/are incorrect about oral cancer?

A. It arises as a primary lesion that originates in any of the tissues in the mouth by metastasis.
B. Oncogenes are activated as a result of mutation of the DNA.
C. Most oral cancers look very similar under the microscope and are called thymic cell carcinoma.

  1. Only A
  2. Only B
  3. Only C
  4. Only A and B
  5. Only B and C
Question 11 Multiple Choice (Single Answer)

Which of the following cancers originate(s) in the lining of the proximal convoluted tubule?

  1. Transitional cell carcinoma
  2. Renal cell carcinoma
  3. Retinoblastoma
  1. Only 1
  2. Only 2
  3. Only 3
  4. Only 1 and 2
  5. Only 2 and 3
Question 12 Multiple Choice (Single Answer)

Which of the following pairs of 'cancer - its place of origin' is incorrectly matched?

  1. Uveal melanoma - eye
  2. Oligodendrogliomas - brain
  3. Adrenocortical carcinoma - cortex
  4. Desmoplastic small round-cell tumor - cervix
  5. Oral cancer - cancer of the lips, tongue, cheeks and floor of the mouth
Question 13 Multiple Choice (Single Answer)

Which of the following cancers originate(s) in the bone marrow, develop(s) in the lymphatic system and normally fight(s) infection by producing antibodies?

  1. Chronic lymphoid leukemia
  2. Cutaneous T-cell lymphoma
  3. Intraocular melanoma
  1. Only 1
  2. Only 2
  3. Only 3
  4. Only 1 and 2
  5. Only 2 and 3
Question 14 Multiple Choice (Single Answer)

Match the following.

 
Column – I Column – II
P. Esophageal cancer 1. Bile ducts
Q. Wilms' tumor 2. Epithelial cells
R. Cholangiocarcinoma 3. Food pipe and gullet
S. Carcinoma 4. Kidneys
  1. P - 4, Q - 3, R - 2, S - 1
  2. P - 3, Q - 4, R - 1, S - 2
  3. P - 1, Q - 3, R - 2, S - 4
  4. P - 2, Q - 4, R - 3, S - 1
  5. P - 2, Q - 3, R - 4, S - 1
Question 15 Multiple Choice (Single Answer)

Which of the following pairs of 'cancer - its description' is incorrectly matched?

  1. Appendiceal cancer - malignancies of the vermiform appendix
  2. Cholangiocarcinoma - bile ducts which drain bile from the liver into the small intestine
  3. Adenoma - tumor of the epithelial tissue with glandular origin
  4. Carcinoid tumor - enterochromaffin cells throughout the gut
  5. Chronic myelogenous leukemia- primary intracranial tumor appearing mostly in patients with severe immunosuppression