Biotechnology (GATE)
Biotechnology BioinformaticsImmunologyBiochemistryMicrobiologyBiomolecules and Their ConformationChemical and Functional Nature of EnzymesProcess BiotechnologyAntibiotics and Pigments etc
Questions
Which of the following is not a pair of equivalent PAM and Blossum matrices?
- PAM100 and Blosum90
- PAM120 and Blosum80
- PAM160 and Blosum60
- PAM200 and Blosum45
- All are equivalent pairs.
Which of the following are protoplast fusion inducing agents?
- Inactivated Sendai virus
- Colchicine
- Polyethylene glycol
- Ca2+ at alkaline pH
- Only 1 and 2
- Only 1, 2 and 3
- Only 1, 3 and 4
- Only 2, 3 and 4
- All are protoplast fusion inducing agents.
Which among the following proteins has the largest number of polypeptide chains?
- Ribonuclease A
- Lysozyme
- Chymotrypsin
- Hexokinase
- Glutamine synthase
Which among the following proteins is made up of five polypeptide chains?
- Myoglobin
- Hemoglobin
- Chymotrypsinogen
- RNA polymerase
- Titin
Which of the following statements are false?
- All T cells originate from haematopoietic stem cells in the bone marrow.
- All the blood grouping reactions are precipitation reactions.
- Idiotypic determinants of an antibody are associated with the variable region.
- The basis for blue-white screening with PUC vectors is intergenic complementation.
- Only 1 and 2
- Only 1 and 4
- Only 2 and 3
- Only 2 and 4
- Only 3 and 4
Which of the following is an example of copper containing metalloprotein?
- Ferritin
- Alcohol dehydrogenase
- Calmodulin
- Dinitrogenase
- Plasocyanin
Which of the following is a pair of ketohexoses?
- Mannose and talose
- Sorbose and psicose
- Arabinose and xylose
- Ribulose and xylulose
- Erythrose and erythrulose
Match the entries in Column I (antibiotics) with that in Column II (their activity spectrum).
| Column I |
</strong>|<strong> Column II</strong>|
|P. Actinomycin D|1. Antiprotozoal|
|Q. Amphotericin B|2. Antitumor|
|R. Rifamycin|3. Antituberculosis|
|S. Tinidazole|4. Antifungal|
- P - 1; Q - 2; R - 3; S - 4
- P - 1; Q - 3; R - 2; S - 4
- P - 2; Q - 4; R - 3; S - 1
- P - 3; Q - 2; R - 4; S - 1
- P - 4; Q - 2; R - 1; S - 3
Match the entries in Column I (amino acid) with Column II (single letter code).
| Column I |
</strong>|<strong>Column II</strong>|
|P. Aspartate|1. N|
|Q. Glutamate|2. Q|
|R. Asparagine|3. D|
|S. Glutamine|4. E|
- P - 1; Q - 2; R - 3; S - 4
- P - 2; Q - 1; R - 4; S - 3
- P - 3; Q - 2; R - 4; S - 1
- P - 3; Q - 4; R - 1; S - 2
- P - 4; Q - 3; R - 2; S - 1
Which of the following statements is/are false regarding peptide linkage?
- C-N bond length in peptide link is intermediate in length between typical carbon-nitrogen single bond and carbon-nitrogen double bond.
- Peptide bond is planar.
- The two alpha-carbon atoms attached to C-N are always cis to each other.
- Only 1
- Only 2
- Only 3
- 1 and 2
- 2 and 3
Which of the following antibiotics is used as a food preservative?
- Nisin
- Seromycin
- Tetracycline
- Candicidin
- Vancomycin
Which of the following is a set of aminoglycoside antibiotics?
- Amikacin, Carbomycin and Kanamycin
- Amikacin, Gentamicin and Kanamycin
- Carbomycin, Erythromycin and Metacycline
- Carbomycin, Erythromycin and Gentamicin
- Erythromycin, Gentamicin and Metacycline
Match the entries in Column I and Column II.
| Column I |
</strong>|<strong> Column II</strong>|
|P. Immunoglobulin G|1. Hemoprotein|
|Q. Casein|2. Flavoprotein|
|R. Succinate dehydrogenase|3. Phosphoprotein|
|S. Hemoglobin|4. Glycoprotein|
- P - 1; Q - 2; R - 3; S - 4
- P - 3; Q - 1; R - 4; S - 2
- P - 4; Q - 2; R - 3; S - 1
- P - 4; Q - 2; R - 1; S - 3
- P - 4; Q - 3; R - 2; S - 1
Match the entries in Column I (protein) and Column II (isoelectric point).
| Column I |
</strong>|<strong>Column II</strong>|
|P. Urease|1. 5.0|
|Q. Hemoglobin|2. 6.8|
|R. Chymotrypsinogen|3. 9.5|
|S. Lysozyme|4. 11.0|
- P - 1; Q - 2; R - 3; S - 4
- P - 2; Q - 1; R - 3; S - 2
- P - 3; Q - 2; R - 4; S - 1
- P - 3; Q - 2; R - 1; S - 4
- P - 4; Q - 3; R - 2; S - 1
Match the entries in Column I (coenzyme) and Column II (its dietary precursor in mammals).
| Column I | Column II |
| P. Coenzyme A | 1. Vitamin B1 |
| Q. Flavinadinine dinucleotide | 2. Vitamin B6 |
| R. Thiamine pyrophosphate | 3. Vitamin B12 |
| S. Pyridoxal phosphate | 4. Vitamin B5 |
- P - 1; Q - 3; R - 2; S - 4
- P - 2; Q - 4; R - 1; S - 3
- P - 3; Q - 4; R - 1; S - 2
- P - 4; Q - 3; R - 1; S - 2
- P - 4; Q - 3; R - 2; S - 1
ASSERTION (A): Gram-positive bacteria are generally resistant to complement-mediated lysis.
REASON (R): In Gram-positive bacteria, thick peptidoglycan layer prevents insertion of membrane attack complex into the inner membrane.
Directions: In the following question there are two statements, Assertion (A) and Reason (R). Consider both the statements independently and mark your answer as under:
1. If A and R both are correct and R is the correct explanation of A
2. If A and R both are correct and R is not the correct explanation of A
3. If A is correct and R is incorrect
4. If A is incorrect and R is correct
5. If A and R both are incorrect
- 1
- 2
- 3
- 4
- 5