Microbiology
Core concepts in microbiology including landmark discoveries, microbial diseases and host-pathogen interactions, virus classification, and prokaryotic and eukaryotic cell structure.
Questions
Who studied the growing fungal colonies from single spores on gelatin surface?
- Brefeld
- J. J. Theophile Schloesing
- Robert Koch
- F. J. Cohn
- John Tyndall
Which of the following is/are the causative microorganism(s) for spirochetes' disease in humans?
1. Chlamydia pneumoniae
2. Borrelia recurrentis
3. Treponema pallidum
4. Leptospira interrogans
- Only 1
- Only 1 and 2
- 1, 2 and 3
- 2, 3 and 4
- Only 4
Who proposed that - "Diseases are caused by microorganisms"?
- Girolamo Fracastoro
- Francesco Redi
- Agostino Bassi
- Robert Koch
- Both (1) and (3)
Which of the following is/are the causing pathogen(s) of Crimean-Congo haemorrhagic fever?
- Rickettsia prowazekii
- Bacillus legionella
- Hantavirus
- Nairovirus
- Only 1
- Only 2
- Both 2 and 3
- Both 3 and 4
- Only 4
Which of the following statements is/are false?
P. The method of sterilisation by discontinuous heating was developed by John Tyndall.
Q. Robert Koch reported microbial culture technique originally.
R. Jacob Lipman reported microscopic worms in the blood of plague victims.
- Only P
- Only Q
- Only R
- Both P and Q
- Both Q and R
Which of the following viruses have helical capsid symmetry?
- Influenza virus A
- Isavirus
- Thogotovirus
- Dengue virus
- Only 1
- Only 3
- Only 1 and 2
- Only 2 and 4
- 1, 2 and 3
Which of the following statements is/are false about Eukaryotic cell?
- The size is between 10-100 mirco-metre.
- Glycocalyx is present in all bacterial cells.
- Cell division involves mitosis phase.
- Sexual reproduction involves meiosis.
- Only (1)
- Only (2)
- Only (4)
- Both (1) and (2)
- Both (3) and (4)
Match the following:
| List - A (Infectious diseases) | List - B (Causing pathogens) |
| P. Bolivian haemorrhagic fever | 1. Machupovirus |
| Q. Diphtheria | 2. Clostridium |
| R. Lyme disease | 3. Corynebacerium |
| S. Tetanus | 4. Borrelia |
| 5. Plasmodium |
- P - 4, Q - 3, R - 5, S - 2
- P - 2, Q - 3, R - 4, S - 1
- P - 1, Q - 3, R - 4, S - 2
- P - 5, Q - 3, R - 2, S - 1
- P - 2, Q - 5, R - 1, S - 4
Match the following:
| Column - I (Infectious fever types) | Column - II (Causative pathogens) |
| P. West Nile fever | 1. Rickettsia rickettsii |
| Q. Rocky Mountain spotted fever | 2. Flavi virus |
| R. Rat-bite fever | 3. Giardia lamblia |
| S. Q fever | 4. Coxiella burnetii |
| 5. Streptobacillus moniliformis |
- P - 2, Q - 1, R - 5, S - 4
- P - 5, Q - 1, R - 2, S - 3
- P - 2, Q - 4, R - 3, S - 1
- P - 5, Q - 3, R - 1, S - 4
- P - 2, Q - 4, R - 5, S - 1
Which of the following statements is//are false?
P. C. L. Alphonse Laveran reported that Neisseria gonorrhoeae causes gonorrhea.
Q. According to Holmes' classification of viruses, Phytophaginae attack on plants.
R. Roger Kornberg received the Nobel Prize in 1974 for the mechanism of transcription in eukaryotes.
- Only P
- Only Q
- Only R
- Both P and Q
- Both Q and R
Which of the following pairs is mismatched?
- Sydney Brenner - work on messenger RNA as site of protein synthesis
- Paul Berg - recombinant DNA technology
- Stanley Prusiner - discovery and characterisation of prions
- Sidney Altman and Thomas Cech - action of restriction enzymes to splice foreign components into DNA
- Kary Mullis - polymerase chain reaction
Which of the following terminologies is/are not correctly matched?
P. Parasitology - Study of parasitism and parasites that include pathogenic protozoa, helminth worms and some insects
Q. Microbial biochemistry - Study of genome of microorganisms and construction of phylogenetic tree based on RNA
R. Agricultural microbiology - Study of relationships of microbes and crops with an emphasis on control of plant diseases and improvement of yields
- Only P
- Only Q
- Only R
- Both P and Q
- Both Q and R
Match the following:
| Group - I |
</strong>|<strong>Group - II </strong>|
|P. Emil von Behring|1. Methods for staining bacteria|
|Q. C. Golgi and S. R. Cajal|2. Serum therapy|
|R. Robert Koch|3. Structure of vestibular apparatus|
|S. Robert Bárány|4. Structure of nervous system|
- P - 2, Q - 4, R - 1, S - 3
- P - 2, Q - 1, R - 4, S - 3
- P - 2, Q - 4, R - 3, S - 1
- P - 1, Q - 3, R - 4, S - 2
- P - 4, Q - 3, R - 1, S - 2
The antibiotic 'cycloserine' is obtained from
- Streptomyces orchidaceus
- Streptomyces fradiae
- Streptomyces orientalis
- Actinoplanes teichomyceticus
- Streptomyces noursei
Match the following:
| Group - I (Human diseases) | Group - II (Causative protozoans) |
| P. African sleeping sickness | 1. Toxoplasma gondii |
| Q. Chaga’s disease | 2. Trypanosoma brucei |
| R. Toxoplasmosis | 3. Plasmodium falciparum |
| S. Malaria | 4. Trypanosoma cruzi |
| 5. Balantidium coli |
- P - 2, Q - 4, R - 1, S - 3
- P - 2, Q - 1, R - 4, S - 3
- P - 2, Q - 4, R - 3, S - 1
- P - 1, Q - 3, R - 4, S - 2
- P - 4, Q - 3, R - 1, S - 2