Organic Chemistry Reagents

Armstrong's acid is a strong acid which is related to toluenesulphonic acid and is used in chemical synthesis. It is sometimes used as a divalent counterion for forming salts of basic drug compounds, as an alternative to the related mesylate or tosylate salts.

Disiamylborane is an organoborane used in organic synthesis to add water to a terminal alkyne, forming an aldehyde via anti-Markovnikov addition. Disiamylborane is relatively unreactive and will not react with triple-bonded carbons that are not at the terminal position.

Benzyltrimethylammonium hydroxide, also known as Triton B or trimethylbenzylammonium hydroxide, is an organic base. It is used in aldol condensation reactions and base-catalyzed dehydration reactions.

N-Bromosuccinimide or NBS is a chemical reagent which is used in radical substitution and electrophilic addition reactions in organic chemistry. NBS can be considered a convenient source of cationic bromine.

Ishikawa's reagent is a fluorinating reagent used in organic chemistry. It is used to convert alcohols into alkyl fluorides and carboxylic acids into acyl fluorides. Aldehydes and ketones do not react with it.

Caesium acetate is an ionic caesium compound often used in organic synthesis especially in Perkin synthesis; formation of unsaturated cinnamic-type acids by the condensation of aromatic aldehydes with fatty acids.

1,1-Carbonyldiimidazole is a white crystalline solid. It is often used for the coupling of amino acids for peptide synthesis and as a reagent in organic synthesis.

Dansyl amide is a reactive fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group. It is also produced as a side-product in the labelling of amino acids with dansyl chloride.

The Cornforth reagent is a strong oxidizing agent which can convert primary and secondary alcohols to ketones. In its chemical structure and functions, it is closely related to other compounds made from hexavalent chromium oxide, such as pyridinium chlorochromate and Collins reagent.

1,8-Diazabicyclo[5.4.0]undec-7-ene or more commonly DBU, is a chemical compound and belongs to the class of amidine compounds. It is used in organic synthesis as a catalyst and complexing ligand and a strong (pKa = 24.34 in acetonitrile) non-nucleophilic base.

Diisopinocampheylborane is an organoborane that is useful for asymmetric synthesis. This colourless solid is the precursor to a range or related reagents. The reagent is mainly used for the synthesis of chiral secondary alcohols.

Hexamethylenetetramine is a heterocyclic organic compound. This white crystalline compound is highly soluble in water and polar organic solvents. It has a cage-like structure similar to adamantane. It is useful in the synthesis of other chemical compounds, e.g. plastics, pharmaceuticals, rubber additives etc.

4-Dimethylaminopyridine is a derivative of pyridine. This colourless solid is a useful nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement, Staudinger synthesis of β-lactams and many more. vv

Ethyl 2-bromoacetate is the ethyl ester of bromoacetic acid. It is used as a lachrymatory agent and tear gas agent for chemical warfare.

2,6-Di-tert-butylpyridine is a pyridine derivative. In organic chemistry, it is used as a hindered base.

(Bis(trifluoroacetoxy)iodo)benzene is a hypervalent iodine compound used as a reagent in organic chemistry. The reagent is used in an acidic modification of the Hofmann rearrangement. One example is the conversion of cyclobutanecarboxamine to cyclobutylamine hydrochloride.

IBX acid or 2-iodoxybenzoic acid is an organic compound used in organic synthesis as an oxidising agent. This Periodinane is especially suited to oxidise alcohols to aldehydes.

Aluminium phosphate is a chemical compound. It is used in cake mixes and in some baking powders as a leavening agent to help baked goods rise. Medicinally it is used as adsorbent for toxoid. It is used industrially as a high-temperature dehydrating agent.

N,N-Dicyclohexylcarbodiimide is an organic whose primary use is to couple amino acids during artificial peptide synthesis. Under standard conditions, it exists in the form of white crystals with a heavy, sweet odour.

Methylmagnesium chloride is a commercially available Grignard reagent. Like methyllithium, it is the synthetic equivalent to the methyl carbanion synthon. It is usually sold as a solution in tetrahydrofuran. Two molecules of tetrahydrofuran (in the upper part of the drawing) coordinate by their oxygen atoms to magnesium.

Tetrahydropyran is the organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. The tetrahydropyran ring system is the core of pyranose sugars.

Hydroxybenzotriazole is an organic compound that is a derivative of benzotriazole. It is mainly used to suppress racemization and improve the efficiency of peptide synthesis. It is a white crystalline powder. Commercial it always contains some water (~11.7% wt as the HOBT monohydrate crystal) because it is explosive.

Dioxolane is an heterocyclic acetal. It is related to tetrahydrofuran by interchange of one oxygen for a CH₂ group. The corresponding saturated 6-membered C₄O₂ rings are called dioxanes. The isomeric 1,2-dioxolane (wherein the two oxygen centers are adjacent) is an peroxide. 1,3-dioxolane is used as a solvent and as a comonomer in polyacetals.

Benzoyl peroxide is an organic compound in the peroxide family. It consists of two benzoyl groups bridged by a peroxide link. It is one of the most important organic peroxides in terms of applications and the scale of its production. Benzoyl peroxide is used as an acne treatment, for improving flour, for bleaching hair and teeth, for polymerising polyester and many other uses.

Carboxybenzyl is an amine protecting group in organic synthesis. It is commonly used in peptide synthesis and is formed by reacting an amine with benzyl chloroformate and a weak base. It is used to protect amines from electrophiles.