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Biotechnology (GATE)

Comprehensive biotechnology quiz covering bioinformatics databases, molecular biology techniques, recombinant DNA technology, signal transduction, and biochemistry for GATE and CSIR NET exam preparation.

15 Questions Published
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Questions

Question 1 Multiple Choice (Single Answer)

____________ are examples of protein-protein interaction databases.

  1. BioGRID and Reactome
  2. STRING and SignaLink 2.0
  3. SignaLink 2.0 and Reactome
  4. BioGRID and STRING
  5. Reactome and STRING
Question 2 Multiple Choice (Single Answer)

Which of the following pairs represents primary databases?

  1. SWISS-PROT and PROSITE
  2. SWISS-PROT and Genbank
  3. PROSITE and Genbank
  4. PROSITE and Pfam
  5. Genbank and Pfam
Question 3 Multiple Choice (Single Answer)

Identify the incorrect matching.

  1. PROSITE: Database of protein families and domains
  2. Reactome: Navigable map of human biological pathways
  3. BRENDA: Comprehensive enzyme information system
  4. PhenomicDB: Database linking human mutations with phenotype
  5. PRINTS: A compendium of protein fingerprints
Question 4 Multiple Choice (Single Answer)

Which of the following is an example of phylogenetic database?

  1. TRANSFAC
  2. RefSeq
  3. ModBASE
  4. TreeBASE
  5. InterPro
Question 5 Multiple Choice (Single Answer)

________ is a bibliographic database.

  1. EMBL
  2. PDB
  3. Sequin
  4. BioOne
  5. ModBase
Question 6 Multiple Choice (Single Answer)

International Nucleotide Sequence Database (INSD) consists of which of the following?

  1. DNA Data Bank of Japan
  2. EMBL
  3. GenBank
  1. Only 1
  2. Only 3
  3. 1 and 2
  4. 2 and 3
  5. 1, 2 and 3
Question 7 Multiple Choice (Single Answer)

International Nucleotide Sequence Database (INSD) consists of which of the following?

  1. DDBJ
  2. VectorBase
  3. European Nucleotide Archive
  4. PROSITE
  5. GenBank
  1. 1, 2 and 3
  2. 1, 3 and 5
  3. 2, 3 and 4
  4. 2, 3 and 5
  5. 3, 4 and 5
Question 8 Multiple Choice (Single Answer)

Identify the false statement(s).

  1. In mismatch correction repair, the parental DNA strand is distinguished from the daughter strand by acetylation.
  2. The basis for blue-white screening with pUC vectors is intraallelic complementation.
  3. Nude mice refers to mice without thymus.
  1. Only 1
  2. Only 2
  3. Only 3
  4. 1 and 2
  5. 1 and 3
Question 9 Multiple Choice (Single Answer)

Choose the correct signal transduction pathway.

a. Hormone
b. 7TM receptor
c. G protein
d. cAMP
e. PKA

  1. a → b → c → d → e
  2. a → c → b → d → e
  3. a → c → d → b → e
  4. a → b → c → e → d
  5. a → c → b → e → d
Question 10 Multiple Choice (Single Answer)

While searching a database for similar sequences, E value depends on all of the following, except

A. sequence length
B. number of sequences in the database
C. scoring system
D. probability from a normal distribution

  1. A
  2. B
  3. B and C
  4. C
  5. C and D
Question 11 Multiple Choice (Single Answer)

Match the scientists in column I with their respective discoveries in column II.

 
Column I 
        </strong>|<strong> Column II</strong>|

|P. Arber, Smith and Nathans|1. Restriction enzymes|
|Q. Sir Alec Jeffreys|2. Polymerase chain reaction|
|R. Kary Mullis|3. DNA fingerprinting|
|S. G. Kohler and C. Milstein|4. Hybridoma technology|

  1. P - 1; Q - 2; R - 3; S - 4
  2. P - 1; Q - 3; R - 2; S - 4
  3. P - 2; Q - 1; R - 3; S - 4
  4. P - 2; Q - 3; R - 4; S - 1
  5. P - 3; Q - 2; R - 4; S - 1
Question 12 Multiple Choice (Single Answer)

Match the entries in column I and column II and select the correct answer.

 
Column I 
        </strong>|<strong>Column II</strong>|

|P. euGenes|1. Weizmann Institute of Science|
|Q. GeneCards|2. Indiana University|
|R. PIR|3. Georgetown University Medical Centre|
|S. ModBase|4. University of California at San Francisco|

  1. P - 1; Q - 2; R - 3; S - 4
  2. P - 1; Q - 3; R - 2; S - 4
  3. P - 2; Q - 1; R - 3; S - 4
  4. P - 2; Q - 1; R - 4; S - 3
  5. P - 4; Q - 2; R - 1; S - 3
Question 13 Multiple Choice (Single Answer)

Match the entries:

 
Group I 
        </strong>|<strong>Group II</strong>|

|P. Glycogen phosphorylase|1. Selenium|
|Q. Glutathione peroxidase|2. Pyridoxal phosphate|
|R. Catalase|3. Heme|
|S. Pyruvate carboxylase|4. Biotin|

  1. P - 1; Q - 2; R - 3; S - 4
  2. P - 1; Q - 3; R - 2; S - 4
  3. P - 2; Q - 1; R - 3; S - 4
  4. P - 2; Q - 1; R - 4; S - 3
  5. P - 3; Q - 2; R - 1; S - 4
Question 14 Multiple Choice (Single Answer)

Match the entries in column I with those in column II.

 
Column I 
        </strong>|<strong>Column II </strong>|

|P. MIT|1. Phosphatidylserine|
|Q. Annexin V|2. Microtubules|
|R. Methotrexate|3. Dihydrofolate reductase|
|S. Taxol|4. Succinate dehydrogenase|

  1. P - 1, Q - 3, R - 4, S - 2
  2. P - 2, Q - 1, R - 4, S - 3
  3. P - 3, Q - 1, R - 4, S - 2
  4. P - 3, Q - 2, R - 4, S - 1
  5. P - 4, Q - 1, R - 3, S - 2
Question 15 Multiple Choice (Single Answer)

Match the following:

 
Group I 
        </strong>|<strong>Group II</strong>|

|P. Nalidixic acid|1. Topoisomerase|
|Q. Erythromycin|2. Peptide chain elongation|
|R. Cephalosporin|3. Peptidoglycan synthesis|
|S. Sulphonamide|4. Folic acid biosynthesis|

  1. P - 1, Q - 2, R - 3, S - 4
  2. P - 2, Q - 1, R - 3, S - 4
  3. P - 4, Q - 1, R - 2, S - 3
  4. P - 3, Q - 4, R - 2, S - 1
  5. P - 3, Q - 4, R - 1, S - 2
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