Life Sciences

GATE Life Sciences preparation quiz covering molecular biology, immunology, genomics, and bioinformatics

15 Questions Published

Questions

Question 1 Multiple Choice (Single Answer)

The part of an antibody that recognizes the anti-genic determinant is called _________.

  1. hapten
  2. paratope
  3. immunogen
  4. allergen
  5. mimotope
Question 2 Multiple Choice (Single Answer)

Which among the following are primary lymphoid organs?

  1. Thymus
  2. Bone marrow
  3. Spleen
  4. Lymph nodes
  5. Mucosa-associated lymphoid tissue
  1. 1 and 2
  2. 1, 2 and 4
  3. 2 and 3
  4. 2, 3 and 5
  5. 4 and 5
Question 3 Multiple Choice (Single Answer)

Which of the following proteins enhances follicle-stimulating hormone (FSH) biosynthesis and secretion?

  1. Bindin
  2. Avidin
  3. Activin
  4. Inhibin
  5. Hyalin
Question 4 Multiple Choice (Single Answer)

Assertion: In capping, methyl guanosine triphosphate is added to the 3'-end of hnRNA.
Reason: In tailing, adenylate residues are added at 5'-end in a template independent manner.

Direction: In the following question there are two statements, Assertion (A) and Reason (R), consider both the statements independently and mark your answers as under:

1. A and R both are correct and R is correct explanation of A.
2. A and R both are correct and R is not correct explanation of A.
3. A is correct and R is incorrect.
4. A is incorrect and R is correct.
5. A and R both are incorrect.

  1. A and R are both correct and R is the correct explanation of A.
  2. A and R are both correct and R is not the correct explanation of A.
  3. A is correct and R is incorrect.
  4. A is incorrect and R is correct.
  5. A and R are both incorrect.
Question 5 Multiple Choice (Single Answer)

Which of the following statements is/are not correct about deoxyribonucleic acid?

  1. Histones are rich in the acidic amino acid moities.
  2. A typical nucleosome contains 200 bp of DNA helix.
  3. The chromatin that is more densely packed and stains dark are called as euchromatin.
  4. Euchromatin is a transcriptionally active chromatin.
  1. 1 and 2
  2. 1 and 3
  3. 1 and 4
  4. 2 and 3
  5. 3 and 4
Question 6 Multiple Choice (Single Answer)

Which of the following terms refers to PCD?

  1. Apoptosis
  2. Necrosis
  3. Entosis
  4. Anoikis
  1. 1 and 2
  2. 1 and 4
  3. 2 and 3
  4. 2 and 4
  5. 3 and 4
Question 7 Multiple Choice (Single Answer)

Which of the following bacteriophages was the first DNA-based genome to be sequenced?

  1. Φ X 174 phage
  2. P1 phage
  3. λ phage
  4. T4 phage
  5. MS2 phage
Question 8 Multiple Choice (Single Answer)

Which of the following statements are not true?

  1. Pseudogenes are inactive copies of protein-coding genes.
  2. About 80% of the human genome consists of repetitive DNA sequences.
  3. The human reference genome is a diploid sequence.
  4. The total length of the human genome is over 3 billion base pairs.
  1. 1 and 2
  2. 1 and 3
  3. 1 and 4
  4. 2 and 3
  5. 2 and 4
Question 9 Multiple Choice (Single Answer)

Which of the following sets represents filamentous bacteriophages?

  1. M13 phage, T12 phage, fd phage
  2. M13 phage, f1 phage, fd phage
  3. T2 phage, f1 phage, fd phage
  4. M13 phage, MS2 phage, f1 phage
  5. MS2 phage, T12 phage, f1 phage
Question 10 Multiple Choice (Single Answer)

Match the column – I with column – II and select the correct option

Column – I
        </strong>|<strong>Column &#x2013; II</strong>|

|A. Heterogeneous nuclear RNA|1. Pol I|
|B. Ribosomal RNA|2. RNAP II and Pol II|
|C. Small nuclear RNA|3. Pol III|

  1. A - 1, B - 2, C - 3
  2. A - 2, B - 1, C - 3
  3. A - 2, B - 3, C - 1
  4. A - 3, B - 2, C - 1
  5. A - 3, B - 1, C - 2
Question 11 Multiple Choice (Single Answer)

Which of the following statements is/are correct about the structure of deoxyribonucleic acid?

  1. It is made of two polynucleotide chains, where the backbone is constituted by sugar-phosphate, and the bases project outside.
  2. The two chains have anti-parallel polarity.
  3. Adenine forms three hydrogen bonds with thymine from opposite strand.
  4. The two chains are coiled in a right-handed fashion.
  1. 1 and 2
  2. 1 and 4
  3. 2 and 3
  4. 2 and 4
  5. 3 and 4
Question 12 Multiple Choice (Single Answer)

Which of the following is a pair of bibliographic databases?

  1. EMBL and PDB
  2. PDB and Sequin
  3. Embase and EMBL
  4. BioOne and PDB
  5. BioOne and Embase
Question 13 Multiple Choice (Single Answer)

The International Nucleotide Sequence Database (INSD) consists of which of the following databases?

  1. DNA Data Bank of Japan
  2. European Nucleotide Archive
  3. GenBank
  4. PROSITE
  5. VectorBase
  1. 1, 2 and 3
  2. 1, 3 and 5
  3. 2, 3 and 4
  4. 2, 4 and 5
  5. 3, 4 and 5
Question 14 Multiple Choice (Single Answer)

Which of the following is an incorrect statement?

  1. PCR is a laboratory technique for amplifying a specific DNA sequence.
  2. Gel electrophoresis is a basic technique used to separate DNA, RNA or proteins.
  3. The northern blotting is a laboratory method used to detect specific RNA molecules from a mixture of RNA molecules.
  4. Electroporation used to transfer polar molecules like DNA into host cells.
  5. The southern blotting technique depends on similarities between the sequences of probe RNA and experimental RNA.
Question 15 Multiple Choice (Single Answer)

Match the column – I with column – II and select the correct option

Column – I
        </strong>|<strong>Column &#x2013; II</strong>|

|A. DDBJ|1. Bibliographic database|
|B. MEDLINE|2. Nucleotide sequence database|
|C. NatureServe|3. Model organism database|
|D. WormBase|4. Biodiversity database|

  1. A - 4, B - 3, C - 2, D - 1
  2. A - 2, B - 1, C - 4, D - 3
  3. A - 2, B - 1, C - 3, D - 4
  4. A - 3, B - 2, C - 4, D - 1
  5. A - 1, B - 2, C - 3, D - 4