Life Sciences
GATE Life Sciences preparation quiz covering molecular biology, immunology, genomics, and bioinformatics
Questions
The part of an antibody that recognizes the anti-genic determinant is called _________.
- hapten
- paratope
- immunogen
- allergen
- mimotope
Which among the following are primary lymphoid organs?
- Thymus
- Bone marrow
- Spleen
- Lymph nodes
- Mucosa-associated lymphoid tissue
- 1 and 2
- 1, 2 and 4
- 2 and 3
- 2, 3 and 5
- 4 and 5
Which of the following proteins enhances follicle-stimulating hormone (FSH) biosynthesis and secretion?
- Bindin
- Avidin
- Activin
- Inhibin
- Hyalin
Assertion: In capping, methyl guanosine triphosphate is added to the 3'-end of hnRNA.
Reason: In tailing, adenylate residues are added at 5'-end in a template independent manner.
Direction: In the following question there are two statements, Assertion (A) and Reason (R), consider both the statements independently and mark your answers as under:
1. A and R both are correct and R is correct explanation of A.
2. A and R both are correct and R is not correct explanation of A.
3. A is correct and R is incorrect.
4. A is incorrect and R is correct.
5. A and R both are incorrect.
- A and R are both correct and R is the correct explanation of A.
- A and R are both correct and R is not the correct explanation of A.
- A is correct and R is incorrect.
- A is incorrect and R is correct.
- A and R are both incorrect.
Which of the following statements is/are not correct about deoxyribonucleic acid?
- Histones are rich in the acidic amino acid moities.
- A typical nucleosome contains 200 bp of DNA helix.
- The chromatin that is more densely packed and stains dark are called as euchromatin.
- Euchromatin is a transcriptionally active chromatin.
- 1 and 2
- 1 and 3
- 1 and 4
- 2 and 3
- 3 and 4
Which of the following terms refers to PCD?
- Apoptosis
- Necrosis
- Entosis
- Anoikis
- 1 and 2
- 1 and 4
- 2 and 3
- 2 and 4
- 3 and 4
Which of the following bacteriophages was the first DNA-based genome to be sequenced?
- Φ X 174 phage
- P1 phage
- λ phage
- T4 phage
- MS2 phage
Which of the following statements are not true?
- Pseudogenes are inactive copies of protein-coding genes.
- About 80% of the human genome consists of repetitive DNA sequences.
- The human reference genome is a diploid sequence.
- The total length of the human genome is over 3 billion base pairs.
- 1 and 2
- 1 and 3
- 1 and 4
- 2 and 3
- 2 and 4
Which of the following sets represents filamentous bacteriophages?
- M13 phage, T12 phage, fd phage
- M13 phage, f1 phage, fd phage
- T2 phage, f1 phage, fd phage
- M13 phage, MS2 phage, f1 phage
- MS2 phage, T12 phage, f1 phage
Match the column – I with column – II and select the correct option
| Column – I |
</strong>|<strong>Column – II</strong>|
|A. Heterogeneous nuclear RNA|1. Pol I|
|B. Ribosomal RNA|2. RNAP II and Pol II|
|C. Small nuclear RNA|3. Pol III|
- A - 1, B - 2, C - 3
- A - 2, B - 1, C - 3
- A - 2, B - 3, C - 1
- A - 3, B - 2, C - 1
- A - 3, B - 1, C - 2
Which of the following statements is/are correct about the structure of deoxyribonucleic acid?
- It is made of two polynucleotide chains, where the backbone is constituted by sugar-phosphate, and the bases project outside.
- The two chains have anti-parallel polarity.
- Adenine forms three hydrogen bonds with thymine from opposite strand.
- The two chains are coiled in a right-handed fashion.
- 1 and 2
- 1 and 4
- 2 and 3
- 2 and 4
- 3 and 4
Which of the following is a pair of bibliographic databases?
- EMBL and PDB
- PDB and Sequin
- Embase and EMBL
- BioOne and PDB
- BioOne and Embase
The International Nucleotide Sequence Database (INSD) consists of which of the following databases?
- DNA Data Bank of Japan
- European Nucleotide Archive
- GenBank
- PROSITE
- VectorBase
- 1, 2 and 3
- 1, 3 and 5
- 2, 3 and 4
- 2, 4 and 5
- 3, 4 and 5
Which of the following is an incorrect statement?
- PCR is a laboratory technique for amplifying a specific DNA sequence.
- Gel electrophoresis is a basic technique used to separate DNA, RNA or proteins.
- The northern blotting is a laboratory method used to detect specific RNA molecules from a mixture of RNA molecules.
- Electroporation used to transfer polar molecules like DNA into host cells.
- The southern blotting technique depends on similarities between the sequences of probe RNA and experimental RNA.
Match the column – I with column – II and select the correct option
| Column – I |
</strong>|<strong>Column – II</strong>|
|A. DDBJ|1. Bibliographic database|
|B. MEDLINE|2. Nucleotide sequence database|
|C. NatureServe|3. Model organism database|
|D. WormBase|4. Biodiversity database|
- A - 4, B - 3, C - 2, D - 1
- A - 2, B - 1, C - 4, D - 3
- A - 2, B - 1, C - 3, D - 4
- A - 3, B - 2, C - 4, D - 1
- A - 1, B - 2, C - 3, D - 4