Metalloenzymes: Metal Cofactors in Enzymes
Questions about metal-containing enzymes and their specific metal cofactors, including iron, zinc, copper, selenium, calcium, magnesium, manganese, and tungsten. Covers enzyme classification, metal binding, and biological functions of metals in enzymatic catalysis.
Questions
Which of the following enzymes contain(s) iron?
- Dopamine hydroxylase
- Tyrosinase
- Catechol dioxygenase
- Only 1
- Only 2
- Only 3
- 1 and 2
- 2 and 3
Which of the following is a pair of zinc-containing enzymes?
- Carboxypeptidase and ATPase
- Carbonic anhydrase and Phosphoglucomutase
- Carbonic anhydrase and Carboxypeptidase
- ATPase and Phosphoglucomutase
- Phosphoglucomutase and Carboxypeptidase
Which of the following enzymes contain both zinc and calcium ions?
P. Alcohol dehydrogenase
Q. Neutral protease
R. DNA polymerase
S. α-Amylase
- P and Q
- P and R
- Q and R
- Q and S
- R and S
Which of the following enzymes acts on peroxide as an acceptor?
- Superoxide dismutase
- Cytochrome c oxidase
- Nitrate reductase
- Catalase
- Glutathione reductase
Which of the following is a selenium-containing enzyme?
- Glutathione peroxidase
- Carbonic anhydrase
- Urease
- Dopamine beta-hydroxylase
- Tyrosinase
Iron is an extremely important transition metal in biology. It helps in performing many different biological functions, such as
- transport of O2 to tissues
- release of O2 to muscle cells
- cofactor to some enzymes
- Only 1
- Only 2
- Only 3
- 1, 2 and 3
- 1 and 2
Which of the following are the example(s) of copper-containing enzymes?
P. Carbonic anhydrases
Q. Ureases
R. Catechol dioxygenases
S. Galactose oxidases
- Only P
- Q and R
- Only R
- Only S
- R and S
Which of the following enzymes contains both zinc and magnesium ions?
- Inorganic pyrophosphatase
- Alkaline phosphatase
- Collagenase
- ATPase
- Alcohol dehydrogenase
Which of the following pairs of metalloenzyme and metal cofactors are incorrectly matched?
P. Tyrosinase : Copper
Q. Urease : Copper
R. Dopamine β-hydroxylase : Nickel
S. Catechol dioxygenase : Iron
- P and Q
- P and S
- Q and R
- Q and S
- R and S
Which of the following is/are tungsten-containing metalloenzyme(s)?
- Formaldehyde ferredoxin oxidoreductase
- Carboxypeptidase A
- Carbon monoxide dehydrogenase
- Only 1
- Only 2
- Only 3
- 1 and 2
- 2 and 3
Match the following:
| Column I | Column II |
| P. Arginase | 1. Zn |
| Q. Phosphotransferase | 2. Mn |
| R. Cytochrome oxidase | 3. Mg |
| S. Alcohol dehydrogenase | 4. Cu |
- P - 1, Q - 2, R - 3, S - 4
- P - 1, Q - 3, R - 4, S - 2
- P - 2, Q - 4, R - 3, S - 1
- P - 2, Q - 3, R - 4, S - 1
- P - 3, Q - 1, R - 4, S - 2
Assertion: Zinc-finger nucleases (ZFNs) are artificial restriction enzymes.
Reason: The DNA-binding domains of individual ZFNs are typically contained between nine and eighteen individual zinc finger repeats.
Directions: In the following question, there are two statements, Assertion (A) and Reason (R). Consider both the statements independently and mark your answer as under:
1. A and R both are correct and R is the correct explanation of A.
2. A and R both are correct and R is not the correct explanation of A.
3. A is correct and R is incorrect.
4. A is incorrect and R is correct.
5. A and R both are incorrect.
- (1)
- (2)
- (3)
- (4)
- (5)