Questions
During evolutionary phase of Holoblast to Embryo, cells start differentiating. During this phase Embryogenesis, Progenitor B-cells are developed in
- fetal thymus gland
- bone marrow
- fetal liver
- all of the above
Nomenclature of antibody classes in mammals is
- based on the component heavy chain classes naming
- based on the component light chain classes naming
- based on the order of their identification
- based on the initials of the scientists, who isolated them first
What will be the survival stance of cell lines, if infected with a microbial injection of Haemophilius influenza?
- Human cell lines will die, while chicken cell lines will survive.
- Human cell lines will survive, while chicken cell lines will die.
- Human cell lines and chicken cell lines both will survive the infection.
- Both the cell lines will be partially infected by the virus.
The immunoglobin, which is structured as dimer or sometimes tetramer along with secretory component (a polypeptide chain) is
- secretory IgG
- IgA
- IgD
- secretory IgA
The genetic transfer of MHC-I and MHC-II genes in humans is governed by
- recombination
- linkage
- crossing over
- all of the above
Which of the following is/are not categorised as “Myeloid Progenitor” (stem cells)?
- Basophil
- Platelets
- Natural killer cells
- Mast cells
Assertion: T-Lymphocytes mature in the Thymus gland.
Reason: Progenitor cells migrate from bone marrow to thymus.
- Assertion and Reason are correct and Reason is the correct explanation of Assertion.
- Assertion and Reason are correct and Reason is not the correct explanation of Assertion.
- Assertion is correct but the Reason is wrong.
- Assertion and Reason both are wrong.
Which of the following do/does not characterise active immunity?
- Immunity achieved by injecting antigens
- Activation of immune system
- Immunity achieved by injecting Ab or Ig reactive T-cells
- All of the above
Match the following macrophages to the site of localisation that they differentiate in.
| MACROPHAGE | SITE |
| I. Kupffer cells | a. Bones |
| II. Splenic macrophages | b. Kidneys |
| III. Osteoclasts | c. White pulp |
| IV. Mesangial cells | d. Liver |
- I - d, II - b, III - c, IV - a
- I - c, II - a, III - b, IV - d
- I - d, II - c, III - a, IV - b
- I - d, II - b, III - a, IV - c
Which of the following statements about the Bursa of fabricius (BOF) is correct?
- BOF is responsible for human immunity and not for chicken's immunity towards the bacterial infection.
- BOF is a vital element of the chicken's immune system, while having no effect on the human systems.
- BOF is a vital element of the chicken's immune system, although it helps in enhancement of human immune response too.
- BOF is responsible for chicken immunity and not for human immunity towards the viral infection.
Multiple coding sequences are inserted in between the genes encoding for MHC-I and MHC-II.
The insertions are genetically engineered so as to prevent any loss of function in individual genes. Such a model is then implemented in the biological offspring of a couple. Unfortunately, the child is born with rudimentary kidneys. A kidney transplant is required and doctors look for an advent match.
Based on the above data, answer the following question.
The doctors should look for matches in
- blood relatives to increase the chances
- outside blood relatives as the MHC expression will be different
- brothers and sisters because they would have got the exact tissue typing match
- parents, as they will be the best possible match in this condition