Oncology and Medical Cancer Biology
Test your knowledge of cancer biology including prostate, ovarian, lung cancers and related medical treatments and management approaches.
Questions
Dipalmitoyl-lecithin (DPL) is a prominent lung surfactant, the deficiency of which causes respiratory distress syndrome. Chemically DPL is
- cerebroside
- ganglioside
- phospholipid
- lipoprotein
Mrs. Bansal is pregnant and has undergone the medical test for estimating L: S ratio of amniotic fluid. The significance of this estimation lies in evaluating
- fetal heart rate
- fetal lung maturity
- fetal maturity
- fetal head size
Aman is suffering from progressive prostate cancer. Which of the following symptoms is rarely associated with this type of cancer?
- Symptomatic anaemia
- Haematemesis
- Acute urinary retention
- Sexual dysfunction
Which of the following is not a side effect of hormone treatment?
- Osteoporosis
- Hot flashes
- Loss of libido
- Myelosuppression
Which of the following statements regarding the treatment of hormone refractory prostate cancer in males is correct?
- Docetaxel and prednisolone have been shown to increase median survival of the prostrate patients by 3 to 4 months .
- Mitoxantrone has been observed to increase median survival of the patient approximately by 1 to 2 months.
- Withdrawing anti-androgen treatment gives no benefits to the sufferers of prostate cancer .
- Intravenous radio-isotope therapy has been observed to increase median survival of the patient by 6 to 8months .
Risk factors for ovarian cancer in females include
- young age
- nulliparity
- multiple pregnancies
- prolonged use of oral contraceptives
In metastatic epithelial ovarian cancer
- ascites usually responds well to diuretics
- frequent bowel obstruction is managed using subcutaneous medication
- opioid analgesics should be avoided
- lymphoedema is rare
Which of the following can be excluded from the category of effective treatment of breathlessness associated with lung cancer?
- Nebulised opioid
- Pleurodesis
- Endobronchial stenting
- Regular doses of short-acting oral morphine
Which of the following statements regarding the management of prostate cancer limited to the prostate gland only is correct?
- Active surveillance is a genuine approach.
- Prostatectomy has been observed to be superior over radiotherapy.
- Radiotherapy causes impotence in about 75% of patients.
- Prostatectomy leads to long term incontinence in about 25 to 30% of patients.
Which of the following statements regarding the treatment of relapsed epithelial ovarian cancer in females is correct?
- Platinum chemotherapy is most suitable for patients who relapse less than 6 months after completion of the therapy.
- The response rate to platinum chemotherapy is approximately 50 to 60% in those who relapse more than 2 years after completion of platinum based first line chemotherapy.
- Most patients are cured with further chemotherapy.
- Many of the sufferers can be cured with further surgery .
Which of the following symptoms is not noticed during ovarian cancer in females?
- Abdominal pain and bloating
- Loss of appetite
- Back pain
- Chest pain
Mesothelioma is an aggressive cancer that destroys the membranes of the lungs. Which of the following statements is true regarding mesothelioma?
- Incidence of mesothelioma is decreasing as a consequence of the ban on use of asbestos.
- It is more common in females.
- All deaths due to mesothelioma should be reported to the coroner.
- Radical surgery is the best treatment of this disease.
Which of the following is true about prostrate cancer in men?
- The lifetime risk of developing it is 10%.
- It is the most common cause of cancer death in males.
- Its incidence rate is falling.
- It regards for approximately 30% of all cancers in men
Which of the following statements regarding the complications of prostate bone metastases in males is correct?
- Most pathological fractures occur as the result of trauma.
- In a sufferer the spinal cord compression is frequently managed by surgery.
- Prophylactic orthopaedic intervention is essential for bone abrasions at high risk of fracture.
- Bisphosphonates are unable to reduce the number of cancer-associated skeletal events in the body.
In metastatic prostate cancer
- the median survival is about 24 months
- hormone therapy produces responses in around 70% of men with bone metastases.
- the median response duration of hormone therapy is 3 to 6 months.
- chemotherapy is the most commonly used systemic treatment of prostrate cancer.