CSIR Life Sciences

Paratope is the portion of antibody, which binds with antigen.

Molecular weight of insulin is more than 1000 daltons. So, it is immunogenic.

Hashimotos thyroiditis is due to TSH stimulation-blocking antibody, which blocks activation of TSH hormone and subsequently bring damage and atrophy of thyroid gland.

Huntington disease is caused by increased number of trinucleotide gene repeats (CAG) leading to increased number of glutamine residues incorporated incorresponding protein.

Mad cow disease is caused by a misfolded protein called prions.

Eocene epoch was the warmest period during cenozoic era.

Birefrigerence is an optical activity. An object manifest birefrigerence by appearing bright when placed between two polarising filters oriented with their respective plane of transmission perpendicular to one another.

Transfer of phosphoryl group from substrate to ADP (Adenosine di nucleotide) result the formation of ATP (Adenosine trinucleotide) is called substrate level phosphorylation.

FAD receives hydrogen from succcinate.

Succinate dehydrogenase complex is the only membrane bound enzyme involved in citric acid cycle.

In this step, GTP is formed.

Affinity chromatography using Nickel can be used to separate protein tagged by histidine.

This enzyme converts fructose 6-phosphate to fructose 1,6-bisphosphate. This is an important enzyme involved in regulation of glycolysis.

This enzyme converts glyceraldehyde 3-phosphate to 1, 3-bisphosphoglycerate. Mg²⁺ is not required for this enzyme.

Condensation of acetyl CoA with oxaloacetate leads to the formation of citrate, which invoves the change in convertion of keto group of oxaloacetate to aldol form. This is known as aldol condensation.