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Cell Nucleus: Structure and Function

Questions about nuclear structure, sub-nuclear bodies, and related cellular processes

15 Questions Published
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Questions

Question 1 Multiple Choice (Single Answer)

The nucleoplasmic veil, a structure inside the nucleoplasm, is made up of

  1. Emerin
  2. Nesprin
  3. LEM-3
  4. Chromatin
Question 2 Multiple Choice (Single Answer)

The cells which are incapable of producing daughter cells lack

  1. ribosomes
  2. cell membrane
  3. nucleus
  4. nuclear membrane
Question 3 Multiple Choice (Single Answer)

Mutation in lamin A/C genes results in

  1. Greenberg dysplasia
  2. Progeria
  3. Mandibuloacral dysplasia with type B lipodystrophy
  4. Emery-Dreifuss muscular dystrophy, X-linked (EDMD)
Question 4 Multiple Choice (Single Answer)

Nucleus was first observed by A. V. Leeuwenhoek in

  1. human red blood cells
  2. sea urchin eggs
  3. salmon red blood cells
  4. orchid flowers
Question 5 Multiple Choice (Single Answer)

Anti-nuclear antibodies (ANA) have been observed in

  1. Ménière's disease
  2. Systemic lupus erythematosus
  3. Restless leg syndrome
  4. Autoimmune uveitis
Question 6 Multiple Choice (Single Answer)

Where does the transcription of rDNA occur?

  1. FC region of nucleolus
  2. FC region or FC-DFC boundary
  3. DFC region
  4. GC-DFC boundary
Question 7 Multiple Choice (Single Answer)

Which of the following statements about nucleus is true?

  1. Nucleus possesses a membrane bound organelle called nucleolus.
  2. Nucleus serves as a power house of the cell.
  3. Cells without a membrane bound nucleus cannot divide.
  4. Nucleus was the first organelle to be discovered.
Question 8 Multiple Choice (Single Answer)

Which of the following processes does not occur in nucleus?

  1. Transcription
  2. Translation
  3. Control of gene expression
  4. Replication
Question 9 Multiple Choice (Single Answer)

Which of the following are the largest sub-units passing through the nuclear pores?

  1. mRNAs
  2. Assembled ribosomal sub-units
  3. Cajal bodies
  4. Splicing speckles
Question 10 Multiple Choice (Single Answer)

Which structure provides aqueous channel through nuclear envelope?

  1. Nuclear basket
  2. Nuclear pores
  3. Nucleosomes
  4. Ribosomes
Question 11 Multiple Choice (Single Answer)

Paraspeckle, a sub-nuclear body, is absent during

  1. telophase
  2. interphase
  3. metaphase
  4. anaphase
Question 12 Multiple Choice (Single Answer)

Promyelocytic leukemia (PML) bodies are found in/on

  1. nucleolus
  2. nucleoplasm
  3. nuclear lamina
  4. chromosomes
Question 13 Multiple Choice (Single Answer)

Small intranuclear rods are seen in

  1. paramyotonia congenita
  2. nemaline myopathy
  3. centronuclear myopathies,
  4. hyperthyroid myopathy
Question 14 Multiple Choice (Single Answer)

Cajal bodies are associated with

  1. DNA replication
  2. transcription
  3. RNA processing
  4. snRNP biogenesis
Question 15 Multiple Choice (Single Answer)

"They are located next to the transcriptionally active chromatin and are hypothesised to be the site of active pre-mRNA processing".

The above statement refers to which sub-nuclear body?

  1. Paraspeckles
  2. Splicing speckles
  3. Perichromatin fibrils
  4. RAFA and PTF domains
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