Metalloenzymes and Metal-Containing Biomolecules (GATE)
Questions cover metal-containing enzymes, proteins, and biological metal ions, focusing on their structure, function, and roles in biological systems
Questions
Which of the following is a tungsten-containing metalloenzyme?
- Formaldehyde ferredoxin oxidoreductase
- Carboxypeptidase A
- Carbon monoxide dehydrogenase
- Only 1
- Only 2
- Only 3
- 1 and 2
- 2 and 3
Iron is an extremely important transition metal in biology. It helps to perform many different biological functions, such as
- transport of O2 to tissues
- release of O2 to muscle cells
- cofactor to some enzymes
- Only 1
- Only 2
- Only 3
- 1 and 2
- 1, 2 and 3
Which of the following statements is/are correct about haemoglobin?
- Each haemoglobin molecule can combine with two oxygen molecules.
- Each haemoglobin molecule contains two globin units with two heme units.
- Deoxy- and oxyhaemoglobin have different colours.
- Only 1
- Only 2
- Only 3
- 1 and 2
- 2 and 3
Pernicious anaemia is one of the obvious symptoms of ________ deficiency.
- molybdenum
- calcium
- nickel
- cobalt
- magnesium
Which of the following is a selenium-containing enzyme?
- Glutathione peroxidase
- Carbonic anhydrase
- Urease
- Dopamine beta-hydroxylase
- Tyrosinase
Which of the following is/are copper-containing enzyme(s)?
P. Carbonic anhydrase
Q. Urease
R. Catechol dioxygenase
S. Galactose oxidase
- Only P
- Q and R
- Only R
- R and S
- Only S
Which of the following are biological functions of Mg(II)?
- Present in chlorophyll and helps in photosynthesis
- Activation of enzymes
- Information carrier
- Osmotic balance
- 1 and 2
- 1, 2 and 3
- 1, 2 and 4
- 2 and 4
- 2, 3 and 4
Match the following:
| Column I | Column II |
| P. Arginase | 1. Zn |
| Q. Phosphotransferase | 2. Mn |
| R. Cytochrome Oxidase | 3. Mg |
| S. Alcohol dehydrogenase | 4. Cu |
- P - 1, Q - 2, R - 3, S - 4
- P - 1, Q - 3, R - 4, S - 2
- P - 2, Q - 4, R - 3, S - 1
- P - 2, Q - 3, R - 4, S - 1
- P - 3, Q - 1, R - 4, S - 2
Which of the following drugs is used to cure cancer?
- Amoxicillin
- Cefuroxime
- Budotitane
- Atenolol
- Bismuth subsalicylate
Which of the following is used as anti-copper agent in Wilson’s disease?
- Tetrathiomolybdate
- Selenium sulphide
- Silver sulfadiazine
- Technetium
- Barium sulphate
Match the entries:
| Elements | Used in the treatment |
| P. Li | 1. Gastritis |
| Q. Pt | 2. Rheumatoid arthritis |
| R. Au | 3. Bipolar disorder |
| S. Bi | 4. Cancer |
- P - 4, Q - 2, R - 1, S - 3
- P - 3, Q - 4, R - 2, S - 1
- P - 2, Q - 3, R - 4, S - 1
- P - 1, Q - 4, R - 2, S - 3
- P - 1, Q - 3, R - 2, S - 4
Which of the following are copper-containing proteins involved in electron transfer?
- Plastocyanins
- Ceruloplasmins
- Amicyanins
- Only 1
- 1 and 3
- Only 2
- 2 and 3
- 1, 2 and 3
Which of the following matchings is/are incorrect?
P. Tyrosinase : Copper
Q. Urease : Copper
R. Dopamine β-hydroxylase : Nickel
S. Catechol dioxygenase : Iron
- P and Q
- P and S
- Q and R
- Q and S
- R and S
Match the following:
| Column I | Column II |
| P. Selenium | 1. Anti-dandruff |
| Q. Magnesium | 2. Antacid |
| R. Antimony | 3. Antileishmaniasis |
| S. Tin | 4. Anti-caries |
- P - 1, Q - 2, R - 3, S - 4
- P - 1, Q - 3, R - 2, S - 4
- P - 2, Q - 1, R - 4, S - 3
- P - 2, Q - 3, R - 1, S - 4
- P - 4, Q - 3, R - 2, S - 1