HIV/AIDS: Virology, Diagnosis, and Treatment
Comprehensive quiz covering HIV virology, transmission, diagnostic tests, antiretroviral therapy, history, and common misconceptions
Questions
The genus to which HIV belongs is
- Epsilonretrovirus
- Deltaretrovirus
- Lentivirus
- Alpharetrovirus
Which of the following groups of cells are destroyed by HIV?
(a) Helper T-cells and killer T-cells
(b) Helper T-cells and B-cells
(c) Helper T-cells, memory T-cells, killer T-cells, cytotoxic T-cells
(d) Helper T-cells, memory T-cells, killer T-cells, cytotoxic T-cells and B-cells
- Option (a)
- Option (b)
- Option (c)
- Option (d)
In which form are lentiviruses transmitted?
- Single stranded DNA virus
- Single stranded negative sense RNA virus
- Single stranded positive sense RNA viruses
- Double stranded RNA virus
gp160, a component of virus envelope protein, is coded by
- rev gene
- env gene
- vif gene
- vpr gene
Which of the following is/are involved in HIV viral genome packaging?
- SLIP element
- LTR regions
- Psi element
- vpu protein
Name the confirmatory test for HIV diagnosis.
- ELISA
- Western blot
- Fluorescent microscopy
- RIA
Which of the following enzymes is not present in HIV virus?
- Integrase
- Protease
- RNA polymerase
- Reverse transcriptase
Which was the first HIV protease inhibitor?
- Ritonavir
- Saquinavir
- Indinavir
- Nelfinavir
Who first discovered HIV case in India?
- Y. R. Gaitonde
- Dr. Suniti Solomon
- Dr. Seema Sahay
- Robert Gallo
Which of the following is an HIV-related myth?
- HIV cannot be transmitted through mosquito bites.
- One can get HIV even after using birth control methods like diaphragms, cervical caps, sponges, spermicides, DepoProvera, Norplant, or the Pill.
- HIV can spread through body fluids like sweat and tears.
- There is a risk for HIV even in oral sex.
What is the estimated life of a person with HIV without treatment (from the day of getting infected)?
- 20 years
- 5 years
- 9-11 years
- 1 year
Which is at present the major target for HIV vaccine efforts?
- Viral genome
- Envelope protein
- Reverse transcriptase enzyme
- Lipid membrane
How many genes does HIV viral genome code for?
- 19 or 20
- 7 or 8
- 9 or 10
- 3 or 4
Reverse transcriptase enzyme is present in
- viral genome
- virus particle
- host cytoplasm
- host nucleus
HIV-2 came into humans from
- common chimpanzee
- sooty mangabeys
- rhesus monkey
- gorilla