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Antibodies (Level : Hard)

Comprehensive quiz on antibody structure, types (IgG, IgM, IgA, IgE, IgD), functions, properties, and clinical applications including molecular weights, half-lives, and immune system roles.

22 Questions Published
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Questions

Question 1 Multiple Choice (Single Answer)

IgG protects the body from infections by several mechanisms, except

  1. agglutination
  2. opsonisation
  3. precipitation
  4. neutralisation
Question 2 Multiple Choice (Single Answer)

Which is the most abundant antibody in human body?

  1. IgM
  2. IgG
  3. IgA
  4. IgE
Question 3 Multiple Choice (Single Answer)

Which antibody is administered to neutralise the effect of snake and scorpion venom?

  1. IgD
  2. IgM
  3. IgA
  4. IgG
Question 4 Multiple Choice (Single Answer)

Which is the first antibody to appear in response to antigens in humans?

  1. IgG
  2. IgM
  3. IgA
  4. IgD
Question 5 Multiple Choice (Single Answer)

Which is the only antibody that can pass through placenta?

  1. IgA
  2. IgG
  3. IgM
  4. IgD
Question 6 Multiple Choice (Single Answer)

Which activity is common to both IgM and IgA?

  1. Complement fixation activity
  2. Agglutination activity
  3. Neutralisation activity
  4. Opsonisation activity
Question 7 Multiple Choice (Single Answer)

Which antibodies activate complement?

  1. IgE and IgA
  2. IgG and IgM
  3. IgG and IgA
  4. IgM and IgA
Question 8 Multiple Choice (Single Answer)

The concentration of IgD is low in serum because

  1. IgD is highly unstable
  2. IgD is membrane bound
  3. IgD is produced in minuscule amounts
  4. IgD is an intracellular antibody
Question 9 Multiple Choice (Single Answer)

In mucosal system, IgA exists as

  1. monomer
  2. dimer
  3. trimer
  4. pentamer
Question 10 Multiple Choice (Single Answer)

The half-life of IgE immunoglobulin increases to 2 weeks if IgE molecules bind to

  1. basophills
  2. plasma cells
  3. mast cells
  4. T-cells
Question 11 Multiple Choice (Single Answer)

The IgM of teleost fish is a

  1. pentamer
  2. hexamer
  3. tetramer
  4. trimer
Question 12 Multiple Choice (Single Answer)

Which antibody is effective against parasitic infections?

  1. IgD
  2. IgE
  3. IgM
  4. IgA
Question 13 Multiple Choice (Single Answer)

Which of the following conditions results in complete lack of antibodies?

  1. Multiple sclerosis
  2. x-Linked agammaglobulinemia
  3. Haemolytic anaemia
  4. x-Linked hypophosphatemia
Question 14 Multiple Choice (Single Answer)

Which antibody is produced in spleen?

  1. IgG
  2. IgA
  3. IgM
  4. IgE
Question 15 Multiple Choice (Single Answer)

In which of the following disorders does IgE level increase?

  1. Congenital rubella
  2. Rheumatoid arthritis
  3. Celiac disease
  4. Pneumonia
Question 16 Multiple Choice (Single Answer)

IgY antibody is found in

  1. mammals
  2. chondrichthyes
  3. teleost fish
  4. birds
Question 17 Multiple Choice (Single Answer)

Which type of proteins are antibodies?

  1. Albumins
  2. Heptaglobin
  3. Glycoproteins
  4. Fibrinogens
Question 18 Multiple Choice (Single Answer)

The Fc region of antibody which gives the ability to an antibody to communicate with the other components of the immune system contains

  1. conserved phosphorylation site
  2. conserved glycosylation site
  3. conserved adenylation site
  4. conserved C-mannosylation site
Question 19 Multiple Choice (Single Answer)

What is the part of an antibody which recognises an antigen called?

  1. Epitope
  2. Paratope
  3. Mimotope
  4. Idiotype
Question 20 Multiple Choice (Single Answer)

Match the columns:

 
Immunoglobulin Molecular weight (in KD)
1.IgG a. 200
2. IgM b. 165
3. IgA c. 900
4. IgE d. 150

  1. | ||
    |---|---|
    |1. IgG|c. 900 KD|
    |2. IgM|d. 150 KD|
    |3. IgA|a. 200 KD|
    |4. IgE|b. 165 KD|

  2. | ||
    |---|---|
    |1. IgG|a. 200 KD|
    |2. IgM|d. 150 KD|
    |3. IgA|c. 900 KD|
    |4. IgE|b. 165 KD|

  3. | ||
    |---|---|
    |1. IgG|b. 165 KD|
    |2. IgM|c. 900 KD|
    |3. IgA|a. 200 KD|
    |4. IgE|d. 150 KD|

  4. | ||
    |---|---|
    |1. IgG|d.150 KD|
    |2. IgM|c. 900 KD|
    |3. IgA|b. 165 KD|
    |4. IgE|a. 200 KD|
Question 21 Multiple Choice (Single Answer)

Which isotype is expressed on the surface of immature B-cells?

  1. IgA+
  2. IgG+
  3. IgM+
  4. IgE+
Question 22 Multiple Choice (Single Answer)

Match the columns
Immunoglobulin 
        </strong>|<strong>Half-life (days)</strong>|

|1. IgG|a. 5|
|2. IgM|b. 5.5|
|3. IgA|c. 2|
|4. IgE|d. 23|

  1. |||
    |---|---|
    |1. IgG|c. 2 days|
    |2. IgM|b.5.5 days|
    |3. IgA|d. 23 days|
    |4. IgE|a. 5 days|
  2. |||
    |---|---|
    |1. IgG|a. 5 days|
    |2. IgM|d. 23 days|
    |3. IgA|c. 2 days|
    |4. IgE|b. 5.5 days|
  3. |||
    |---|---|
    |1. IgG|d. 23 days|
    |2. IgM|a.5 days|
    |3. IgA|b. 5.5 days|
    |4. IgE|c. 2 days|
  4. |||
    |---|---|
    |1. IgG|b. 5.5 days|
    |2. IgM|a. 5 days|
    |3. IgA|d. 23 days|
    |4.IgE|c. 5.5 days|
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