Multiple choice What does independent assortment refer to? the separation of alleles in anaphase I the random arrangement of chromosomal tetrads at metaphase I the separation of chromatids at anaphase II the random arrangement of gene loci on a chromosome Reveal answer Fill a bubble to check yourself A Correct answer Explanation Independent assortment occurs during meiosis I when homologous chromosome pairs align randomly at the metaphase plate, leading to the independent distribution of alleles into gametes.