Multiple choice Who fought against each other in the French and Indian War (1754 - 1763)? France against Native Americans? Great Britain against Native Americans? The British colonies against French colonies American Soldiers of French descent against Native Americans Reveal answer Fill a bubble to check yourself C Correct answer Explanation The French and Indian War was the North American theater of the Seven Years' War, pitting the British colonies and their mother country against the French colonies and their indigenous allies.