Multiple choice Activator for Isocitrate Dehydrogenase Mn+2 Mg+2 Zn+2 Fe+2 Reveal answer Fill a bubble to check yourself A Correct answer Explanation Isocitrate dehydrogenase is a key regulatory enzyme in the Krebs cycle that requires divalent metal ions, specifically Manganese (Mn+2) or Magnesium (Mg+2), for its catalytic activity.