Multiple choice Where can ribosomes be located at in the cell? Smooth ER Rough ER Roaming aroung Both in the Rough ER and roaming aroud Reveal answer Fill a bubble to check yourself D Correct answer Explanation Ribosomes can be found in two main locations within a eukaryotic cell: bound to the membrane of the rough endoplasmic reticulum, or floating freely as free ribosomes in the cytoplasm.