Multiple choice Halsted was famous for the following discovery: microbes (germs) could cause disease and could be spread chemicals can be used to reduce the spread of microbes specific microbes cause specific disease Using gloves during surgery can reduce the spread of germs Reveal answer Fill a bubble to check yourself D Correct answer Explanation William Halsted is famous for introducing the use of sterile rubber gloves during surgery. This innovation was a major advancement in preventing the transmission of germs between surgeons and patients.