Multiple choice general knowledge science & technology White blood cells, or leukocytes, make up about 1% of blood. True False Reveal answer Fill a bubble to check yourself A Correct answer Explanation White blood cells (leukocytes) typically make up about 1% of total blood volume by count. The vast majority of blood cells are red blood cells (erythrocytes), which make up about 40-45% of blood volume, with the remainder being plasma and platelets.