The question asks for the biggest away win in Premier League history. While there have been 9-0 away wins (Manchester United vs Southampton 2021, Nottingham Forest vs Arsenal 2024), the 8-1 scoreline has occurred multiple times as an away result, including Newcastle vs Sheffield Wednesday in 1999 and Chelsea vs Aston Villa in 2012. Among the given options, 8-1 is the correct answer as it represents the largest away victory margin available.