Multiple choice

Which of the following are consensus-based gene prediction programs?

  1. GenomeScan
  2. EST2Genome
  3. SGP-1
  4. GeneComber
  5. DIGIT

  1. 1, 2 and 3

  2. 2 and 4

  3. 3 and 4

  4. 3, 4 and 5

  5. 4 and 5

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Consensus-based gene prediction programs Because different prediction programs have different levels of sensitivity and specificity, it makes sense to combine results of multiple programs based on consensus. GeneComber is a web server that combines HMMgene and GenScan prediction results. DIGIT is another consensus-based web server. It uses prediction from three ab initio programs – FGENESH, GENSCAN, and HMMgene.