Multiple choice

The antibody diversity is generated by the following mechanisms. Which of the following mechanisms plays role in B cell antibody diversity, but not in T cells antibody diversity?

  1. Multispecificity

  2. Combinatorial association

  3. Somatic mutation

  4. N region insertion

  5. V-J and V-D-J joining

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Diversity in the T cell receptor is also generated in the same way as for B cell antibody diversity, e.g., by VJ and VDJ joining of gene segments and combinatorial association. However, no somatic mutation has been observed in T cells.