Multiple choice

Which of the following enzymes breaks the phosphodiester bond within a polynucleotide?

  1. Exonucleases

  2. Topoisomerases

  3. Endonucleases

  4. Helicases

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain, in contrast to exonucleases, which cleave phosphodiester bonds at the end of a polynucleotide chain.