Multiple choice The digestive hormone produced by cells of the duodenum is Gastrin Secretin CCK (cholecystokinin) GIP (Gastric Inhibitory Peptide) Reveal answer Fill a bubble to check yourself B Correct answer Explanation Secretin is produced by cells of the duodenum. Its production is stimulated by acid chyme from stomach. It stimulates the pancreas to produce sodium bicarbonate, which neutralizes the acidic chyme. It also stimulates the liver to secrete bile.