Multiple choice

The sensation of fatigue in the muscles after prolonged strenuous physical work, is caused by

  1. a decrease in the supply of oxygen

  2. minor wear and tear of muscle fibres

  3. the depletion of glucose

  4. the accumulation of lactic acid
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D Correct answer
Explanation

The reduction in force of contraction of a muscle after prolonged stimulation is called muscle fatigue. The accumulation of lactic acid leads to muscle fatigue. Lactic acid is produced by glycolysis in the absence of O2.

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