It is made up of three segments — the duodenum, jejunum, and ileum .It is a 22-foot long muscular tube that breaks down food using enzymes released by the pancreas and bile from the liver. Peristalsis also is at work in this organ, moving food through and mixing it with digestive secretions from the pancreas and liver. The duodenum is largely responsible for the continuous breaking-down process , with the jejunum and ileum mainly responsible for absorption of nutrients into the bloodstream.