Multiple choice

Which of the following statements does not characterise non-nucleoside reverse transcriptase inhibitors in an individual suffering from AIDS?

  1. They cannot be used parallel to nucleoside reverse transcriptase inhibitors.

  2. They get attached to an allosteric binding site.

  3. Resistance can be created due to a mutation resullting asparagine in the target binding site changed into lysine.

  4. Binding of NNRTIs with the main protein chain in the binding site slowers the reaction.

  5. They interfere with reverse transcriptase by binding indirectly to the enzyme.
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The non-nucleoside reverse transcriptase inhibitors bind to an allosteric binding site next to the active site of reverse transcriptase.

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