Multiple choice

Which of the following is found in the amyloid deposits found in 10–20% of patients with myeloma?

  1. Immunoglobulin light chains

  2. Immunoglobulin heavy chains

  3. Amyloid A (AA) protein

  4. Isolated single molecules

  5. Congo red
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A Correct answer
Explanation

Immunoglobulin-secreting cells produce an excess of light chain over heavy chain. Fragments of this excess light chain form the amyloid deposits found in 10–20% of patients with multiple myeloma.

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