Multiple choice

The circulating plasma protein which participates in the initiation of blood coagulation is known as high molecular weight kininogen (HMWK). Which of the following is the other name of HMWK?

  1. FSF

  2. AHF

  3. Proaccerin

  4. Hageman factor

  5. Fitzgerald factor

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

High molecular weight kininogen is also known as Fitzerland factor. In the past, HMWK has been called HMWK-kallikrein factor, Flaujeac factor (1975), Fitzgerald factor (1975) and Williams-Fitzgerald-Flaujeac factor, the eponyms being for people first reported to have HMWK deficiency. Its current accepted name is to contrast it with low molecular weight kininogen (LMWK), which has a similar function to HMWK in the tissue (as opposed to serum) kinin-kallikrein system.