Multiple choice

Which of the following diseases in an infant is not a manifestation of maternal IgG antibody crossing the placenta?  

  1. Myaesthenia gravis

  2. Malar rash

  3. HIV infection

  4. Thyrotoxicosis

  5. Haemolytic disease of the newborn.

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

HIV infection is due to transmission of the HIV virus, not the antibody. However, the presence of maternal anti-HIV IgG can lead to diagnostic difficulty. It is therefore necessary to confirm HIV infection in the newborn by the presence of viral DNA or RNA using a polymerase chain reaction (PCR) method.