Which of the following are phylogenetic footprinting–based methods?
P. ConSite
Q. PromH(W)
R. MEME
S. AlignACE
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Only P and Q
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Only P and R
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Only P and S
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Only Q and R
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Only R and S
A
Correct answer
Explanation
Phylogenetic Footprinting–Based Method
The identification of conserved noncoding DNA elements that serve crucial functional roles is referred to as phylogenetic footprinting; the elements are called phylogenetic footprints. This type of method can apply to both prokaryotic and eukaryotic sequences.
ConSite is a web server that finds putative promoter elements by comparing two orthologous sequences.
PromH(W) is a web-based program that predicts regulatory sites by pair- wise sequence comparison.