Multiple choice

In which site are M cells found in the intestine?  

  1. Interacting with intraepithelial lymphocytes

  2. In the lamina propria

  3. In the follicles of the Peyer's patches

  4. In the dome area of Peyer's patches

  5. Within the parvocellular layers of the lateral geniculate nucleus of the thalamus
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D Correct answer
Explanation

Peyer's patches are covered by specialized epithelium (follicle-associated epithelium). Some of these epithelial cells have surfaces, which seem folded under the scanning electron microscope. These microfold, or M cells, sample and actively transport particulate antigens from the lumen into the ‘dome’ area, where priming of both T and B lymphocytes occurs.

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