Multiple choice

Considering acid-base regulation in the body, which of the following statements are true?

  1. Overall human metabolism results in acid production.

  2. Buffers must be strong acids or bases.

  3. Carbon dioxide directly raises the pH of body fluids.

  4. The pH of a buffer solution is always 7.0.

  5. A decrease in the plasma level of bicarbonate ions (HCO3-) will directly raise the pH of plasma.
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A Correct answer
Explanation

Overall, the body is a net producer of acid and a major function of the kidney is to excrete this acid load. A large change in body pH cannot be tolerated as it will have adverse effects on cellular function.

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