Multiple choice

Which of the following statements concerning sodium ions in the nephron is correct?

  1. The concentration of sodium ions is generally higher inside the cells than outside the cells.

  2. Sodium is not filtered in the glomerulus.

  3. Most sodium is reabsorbed in the distal tubule.

  4. There is no active transport of sodium.

  5. The diuretic drug furosemide blocks the NaK2Cl channel in the loop of henle.
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E Correct answer
Explanation

If drugs are given which inhibit sodium reabsorption, then there is more sodium in the tubules and this means that more water stays in the tubules with it because of the osmotic effect of the sodium. Such drugs are known as diuretics because they increase the amount of water excretion. Diuretics such as furosemide (frusemide) inhibit sodium reabsorption in the loop of henle, drugs such as the thiazides oppose sodium reabsorption in the distal tubule and drugs such as amiloride oppose sodium reabsorption in the collecting ducts.

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