Majority of proteins are the most variable and highly specialized enzymes. Acting as organic catalysts, they accelerate metabolic reactions. Virtually, every type of metabolic reaction is driven by a particular or specific type of enzyme. In fact, the basis of the phenotypic expression of every hereditary characteristic is a specific type of metabolic reaction which in turn, is driven by a specific type of enzyme. Synthesis of defective or abnormal enzymatic proteins, therefore, forms the basis of genetic diseases.