Multiple choice

Which of the following mast cell products is not preformed and therefore has to be newly synthesised?

  1. Histamine

  2. Prostaglandin D2

  3. Heparin

  4. Neutral protease

  5. Eosinophil chemotactic factor (ECF)
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Prostaglandins and thromboxanes are newly synthesised by the mast cell using the cyclo-oxygenase pathway. The leukotrienes B4, C4 and D4 (slow reacting substance of anaphylaxis, SRS-A) are also newly synthesised by the mast cell, in this instance using the lipoxygenase pathway.

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