Multiple choice

Which of the following drugs was first used in the treatment of syphilis?

  1. Aarsphenamine

  2. Bithionol

  3. Nardil

  4. Terfenaldine

  5. Serotonin
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A Correct answer
Explanation

Arsphenamine, also known as Salvarsan and compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, and was also used to treat trypanosomiasis. It is an organo-arsenic molecule, and was the first modern chemotherapeutic agent. Sahachiro Hata and Paul Ehrlich discovered the antisyphilitic activity of this compound in 1909 in Erlich's laboratory, during a survey of hundreds of newly synthesised organic arsenical compounds.

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