Multiple choice

Mental retardation in man, associated with sex chromosomal abnormality, is usually due to

  1. reduction in X complement

  2. increase in X complement

  3. moderate increase in Y complement

  4. large increase in Y complement
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

An increase in the number of X chromosomes (X complement), such as in Klinefelter syndrome (XXY) or Triple X syndrome (XXX), is often associated with cognitive deficits and mental retardation. While Y chromosome abnormalities exist, the X complement has a more pronounced effect on neurodevelopmental outcomes.

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