Multiple choice _________ helps to manufactured proteins, fat molecules or lipids. Vacuoles Golgi apparatus Endoplasmic reticulum Plastids Reveal answer Fill a bubble to check yourself C Correct answer Explanation The Endoplasmic Reticulum (ER) is responsible for the synthesis of essential biomolecules. Rough ER, which has ribosomes attached, manufactures proteins, while Smooth ER is the primary site for lipid and fat molecule production.