Multiple choice

Which of the following statements regarding the replication of Ebolavirus is incorrect?

  1. Replication presumably starts when enough nucleoprotein is present.

  2. Fusion of virus membrane with the vesicle membrane is triggered by either low pH or NPC1 binding.

  3. The virion enters early endosomes by Micropinocytosis.

  4. In some culture cells, GP glycoprotein can be processed by host Cathepsin L and Cathepsin B into 19kDa GP1.

  5. Sequential transcription, and viral mRNAs are capped.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

The virion enters early endosomes by Macropinocytosis.Attachment to host receptors through GP glycoprotein mediates is endocytosed into vesicles in the host cell. Host DC-SIGN and DC-SIGNR play a role in virion attachment.

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