Multiple choice

Abnormally folded prion proteins are generally

  1. relatively sensitive to protease digestion

  2. associated with CGD

  3. present in follicular dendritic cells in individuals with transmissible spongiform encephalopathies

  4. normally eliminated by B-cells

  5. destroyed by macrophages
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

FDCs naturally express high levels of the normal prion protein which then becomes abnormal following exposure to the transmissible spongiform encephalopathy (TSE) agent.

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